Anemia and brain hypoxia.
作者信息
Wood John C
机构信息
Children's Hospital Los Angeles.
出版信息
Blood. 2023 Jan 26;141(4):327-328. doi: 10.1182/blood.2022018229.
Abstract
摘要
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Anemia and brain hypoxia.贫血与脑缺氧。
Blood. 2023 Jan 26;141(4):327-328. doi: 10.1182/blood.2022018229.
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Letter: Possible precipitation of cerebral thrombosis in sickle-cell anemia by hyperventilation.信函：换气过度可能诱发镰状细胞贫血患者的脑血栓形成。
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Normalization of cerebral hemodynamics after hematopoietic stem cell transplant in children with sickle cell disease.儿童镰状细胞病造血干细胞移植后脑血流动力学的正常化。
Blood. 2023 Jan 26;141(4):335-344. doi: 10.1182/blood.2022016618.
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Cerebral oxygen metabolic stress is increased in children with sickle cell anemia compared to anemic controls.与贫血对照相比，镰状细胞贫血患儿的脑氧代谢应激增加。
Am J Hematol. 2022 Jun 1;97(6):682-690. doi: 10.1002/ajh.26485. Epub 2022 Feb 14.
3
Impairment of Cerebrovascular Hemodynamics in Patients With Severe and Milder Forms of Sickle Cell Disease.重度和轻度镰状细胞病患者的脑血管血流动力学损害
Front Physiol. 2021 Apr 20;12:645205. doi: 10.3389/fphys.2021.645205. eCollection 2021.
4
White matter has impaired resting oxygen delivery in sickle cell patients.白质在镰状细胞病患者中存在静息氧输送受损。
Am J Hematol. 2019 Apr;94(4):467-474. doi: 10.1002/ajh.25423. Epub 2019 Feb 21.
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Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow.镰状细胞病中的无症状梗死发生在边缘区域，与脑血流低有关。
Blood. 2018 Oct 18;132(16):1714-1723. doi: 10.1182/blood-2018-04-841247. Epub 2018 Jul 30.
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Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease.区域性氧摄取量可预测镰状细胞病中边缘带对中风的易损性。
Neurology. 2018 Mar 27;90(13):e1134-e1142. doi: 10.1212/WNL.0000000000005194. Epub 2018 Mar 2.
7
Determinants of resting cerebral blood flow in sickle cell disease.镰状细胞病静息脑血流量的决定因素。
Am J Hematol. 2016 Sep;91(9):912-7. doi: 10.1002/ajh.24441. Epub 2016 Jul 4.
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Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia.镰状细胞贫血症无症状脑梗死输血对照试验。
N Engl J Med. 2014 Aug 21;371(8):699-710. doi: 10.1056/NEJMoa1401731.
9
Low-shear red blood cell oxygen transport effectiveness is adversely affected by transfusion and further worsened by deoxygenation in sickle cell disease patients on chronic transfusion therapy.低切变率下的红细胞氧输送效率会受到输血的不利影响，而在慢性输血治疗的镰状细胞病患者中，脱氧会进一步恶化这种情况。
Transfusion. 2013 Feb;53(2):297-305. doi: 10.1111/j.1537-2995.2012.03822.x. Epub 2012 Aug 6.
10
Red blood cell aggregation, aggregate strength and oxygen transport potential of blood are abnormal in both homozygous sickle cell anemia and sickle-hemoglobin C disease.在纯合子镰状细胞贫血和镰状-血红蛋白C病中，红细胞聚集、聚集强度及血液的氧运输潜力均异常。
Haematologica. 2009 Aug;94(8):1060-5. doi: 10.3324/haematol.2008.005371.
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