J-CREST 多中心队列研究：237 例外源性眼内炎日本患者致盲的危险因素。
Risk Factors for Legal Blindness in 237 Japanese Patients with Exogenous Endophthalmitis: A Multicenter Cohort Study from J-CREST.
机构信息
J-CREST (Japan Clinical Retina Study group), Kagoshima, Japan.
Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya, Japan.
出版信息
Ocul Immunol Inflamm. 2024 Sep;32(7):1133-1141. doi: 10.1080/09273948.2023.2165111. Epub 2023 Jan 26.
PURPOSE
We investigated potential risk factors for visual prognosis in Japanese patients with exogenous endophthalmitis.
METHODS
In this retrospective observational multicenter cohort study, risk factors for legal blindness at 12 weeks after treatment initiation were evaluated based on patient characteristics, initial BCVA, causative events, pathogens, ocular symptoms, duration from symptom onset to initial treatment, and selected treatments.
RESULTS
Overall, 23.1% of eyes developed legal blindness. The six risk factors for legal blindness were presence of eye pain, pathogen identification, poor BCVA at the initial visit, longer duration from symptom onset to initial treatment, type of causative event, and type of causative pathogen. Regarding the type of causative pathogen, coagulase-negative staphylococci was associated with a better visual impairment outcome.
CONCLUSION
Exogenous endophthalmitis remains a severe ocular infection; however, it can be managed with rapid treatment, as well as other advances in medical knowledge and technology.
目的
我们研究了日本外源性眼内炎患者视觉预后的潜在危险因素。
方法
在这项回顾性观察性多中心队列研究中，根据患者特征、初始最佳矫正视力（BCVA）、病因事件、病原体、眼部症状、从发病到初始治疗的时间以及选择的治疗方法，评估了治疗开始后 12 周时失明的法律风险因素。
结果
总体而言，23.1%的眼睛出现法律失明。导致法律失明的六个危险因素是眼痛、病原体鉴定、初始就诊时 BCVA 较差、从发病到初始治疗的时间较长、病因事件的类型和病因病原体的类型。关于病因病原体的类型，凝固酶阴性葡萄球菌与视力损害结局较好相关。
结论
外源性眼内炎仍然是一种严重的眼部感染；然而，通过快速治疗以及医学知识和技术的其他进步，可以对其进行管理。
Zotero 插件