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6-(Arylaminomethyl) Isoquinolines as Enzyme Inhibitors and Their Preparation: A Patent Highlight of Factor XIIa Inhibitors.

作者信息

Al-Horani Rami A

机构信息

Division of Basic Pharmaceutical Sciences, College of Pharmacy, Xavier University of Louisiana, New Orleans LA 70125, USA.

出版信息

Cardiovasc Hematol Agents Med Chem. 2023;21(3):243-249. doi: 10.2174/1871525721666230126114224.

DOI:10.2174/1871525721666230126114224

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10501477/

Abstract

摘要

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[7]

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引用本文的文献

[1]

Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors.

J Thromb Thrombolysis. 2024-12

[2]

New Triazole-Based Potent Inhibitors of Human Factor XIIa as Anticoagulants.

ACS Omega. 2024-2-22

本文引用的文献

[1]

Plasma kallikrein-kinin system contributes to peripheral inflammation in temporal lobe epilepsy.

J Neurochem. 2019-7-10

[2]

Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.

Acta Crystallogr D Struct Biol. 2019-6-4

[3]

Angioedema in Stroke Patients With Thrombolysis.

Stroke. 2019-6-11

[4]

Air Pollution and Angioedema.

Otolaryngol Head Neck Surg. 2019-4-30

[5]

Genetic Variation of Kallikrein-Kinin System and Related Genes in Patients With Hereditary Angioedema.

Front Med (Lausanne). 2019-2-21

[6]

Identification of the recently described plasminogen gene mutation p.Lys330Glu in a family from Northern Germany with hereditary angioedema.

Clin Transl Allergy. 2019-2-14

[7]

Hemilingual Angioedema after Thrombolysis in a Patient on an Angiotensin II Receptor Blocker.

J Stroke Cerebrovasc Dis. 2019-5

[8]

Angioedema after thrombolysis with tissue plasminogen activator: an airway emergency.

Oxf Med Case Reports. 2019-1-24

[9]

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release.

Proc Natl Acad Sci U S A. 2018-12-17

[10]

Factor XII truncation accelerates activation in solution.

J Thromb Haemost. 2018-12-10

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