Parirokh Masoud, Hatami Nima, Nakhaee Nouzar, Abbott Paul V
Endodontology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Iran Endod J. 2022;17(4):165-171. doi: 10.22037/iej.v17i4.37438.
This study aimed to determine the success rate of the combination of buccal infiltration (BI) and inferior alveolar nerve block (IANB) injections in irreversible pulpitis in mandibular molars after premedication with ibuprofen.
From 132 patients participated in the study, 120 patients were included. One hour before root canal treatment, patients with mandibular molars with symptomatic irreversible pulpitis received either a 600 mg ibuprofen capsule or a placebo. All patients received 2% lidocaine with 1:80000 epinephrine and 4% articaine with 1:100000 epinephrine for IANB and BI, respectively. Patients' pain was evaluated using the Heft-Parker visual analog scale during the preparation of access cavity, exposure of pulp, and instrumentation of root canal. The success of anesthesia was defined as the absence of pain or mild pain. The Chi-square and -test were employed for data analysis.
The difference between patient age and gender in the two groups was not significant (>0.05). The anesthesia success rate was 85% in the premedicated and 70% in the placebo group, with statistically significant results (=0.049).
Based on this triple-blinded randomized clinical study, mandibular molars with irreversible pulpitis were not thoroughly anesthetized by a combination of IANB+BI after premedication with ibuprofen (600 mg), even though anesthesia success was improved significantly by ibuprofen premedication
本研究旨在确定在下颌磨牙不可逆性牙髓炎患者中，布洛芬预处理后颊侧浸润（BI）和下牙槽神经阻滞（IANB）联合注射的成功率。
132名参与研究的患者中，120名被纳入。在根管治疗前一小时，有症状的下颌磨牙不可逆性牙髓炎患者服用600毫克布洛芬胶囊或安慰剂。所有患者分别接受含1:80000肾上腺素的2%利多卡因和含1:100000肾上腺素的4%阿替卡因进行IANB和BI注射。在制备开髓腔、暴露牙髓和根管预备过程中，使用赫夫特 - 帕克视觉模拟量表评估患者疼痛程度。麻醉成功定义为无痛或轻度疼痛。采用卡方检验和t检验进行数据分析。
两组患者年龄和性别差异无统计学意义（P>0.05）。预处理组麻醉成功率为85%，安慰剂组为70%，结果具有统计学意义（P = 0.049）。
基于这项三盲随机临床研究，布洛芬（600毫克）预处理后，IANB + BI联合应用不能使下颌磨牙不可逆性牙髓炎患者完全麻醉，尽管布洛芬预处理显著提高了麻醉成功率。
