收治于三级护理中心的 COVID-19 患者中 D-二聚体升高：一项描述性横断面研究。
Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
机构信息
Department of Medicine, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.
Pharmacy Programme, Gandaki University, Pokhara, Kaski, Nepal.
出版信息
JNMA J Nepal Med Assoc. 2022 Jul 1;60(251):596-599. doi: 10.31729/jnma.7579.
INTRODUCTION
Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre.
METHODS
This descriptive cross-sectional study was conducted in COVID-19 unit of a tertiary care centre from 23 January 2021 to 19 June 2021. The ethical approval was taken from the Institutional Review Committee (Reference number: 077/078/159). D-dimer values and demographic data of the hospital-admitted COVID-19 patients were recorded. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated.
RESULTS
Out of 180 patients with COVID-19 admitted in the hospital, the D-dimer levels were raised in 85 (47.22%) (39.93-54.51, 95% Confidence Interval) patients.
CONCLUSIONS
The prevalence of raised D-dimer among admitted COVID-19 patients was found to be lower when compared to other studies conducted in similar settings.
KEYWORDS
COVID-19; D-dimer; Nepal; prevalence.
简介
COVID-19 患者的特征是炎症生物标志物水平异常。COVID-19 患者中 D-二聚体升高与死亡率增加相关。本研究旨在探讨三级护理中心 COVID-19 患者中 D-二聚体升高的发生率。
方法
本研究为 2021 年 1 月 23 日至 6 月 19 日在三级护理中心的 COVID-19 病房进行的描述性横断面研究。该研究获得了机构审查委员会的伦理批准（参考编号：077/078/159）。记录了住院 COVID-19 患者的 D-二聚体值和人口统计学数据。采用方便抽样技术。计算了点估计值和 95%置信区间。
结果
在住院的 180 名 COVID-19 患者中，有 85 名（47.22%）（39.93-54.51，95%置信区间）患者的 D-二聚体水平升高。
结论
与在类似环境中进行的其他研究相比，发现住院 COVID-19 患者中 D-二聚体升高的发生率较低。
关键词
COVID-19；D-二聚体；尼泊尔；流行率。
Zotero 插件