多普勒闪烁伪影诊断尿路结石的准确性：系统评价和荟萃分析。
Diagnostic accuracy of Doppler twinkling artifact for identifying urolithiasis: a systematic review and meta-analysis.
机构信息
Department of Diagnostic Radiology, School of Medicine, University of Phayao, Phayao, Thailand.
Division of Clinical Pharmacy, Department of Pharmaceutical Care, School of Pharmaceutical Sciences, University of Phayao, Phayao, Thailand.
出版信息
J Ultrasound. 2023 Jun;26(2):321-331. doi: 10.1007/s40477-022-00759-z. Epub 2023 Jan 27.
OBJECTIVE
The goal of this study was to perform a comprehensive meta-analysis to assess the overall diagnostic value of Doppler twinkling for the diagnosis of urolithiasis.
METHODS
We systematically searched the PubMed, EMBASE, and Cochrane Library databases from inception through May 31, 2021. Studies including patients with urolithiasis who underwent color flow Doppler sampling to highlight the twinkling artifact and computed tomography were included. Diagnostic test meta-analysis was performed with a bivariate model. We used summary receiver operating characteristic curves to summarize the overall diagnostic performance. The weighted sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were calculated.
RESULTS
Sixteen studies involving 4572 patients were included in the systematic review and meta-analysis. The weighted sensitivity was 0.86 (95% confidence interval [CI] 0.72-0.94), specificity 0.92 (95% CI 0.75-0.98), positive likelihood ratio 11.3, negative likelihood ratio 0.2, and diagnostic odds ratio 75.5.
CONCLUSION
The Doppler twinkling artifact has good diagnostic value for the diagnosis of urolithiasis and should be used as a complementary tool in the diagnosis of urolithiasis.
目的
本研究旨在进行全面的荟萃分析，以评估多普勒闪烁在诊断尿路结石中的总体诊断价值。
方法
我们系统地检索了 PubMed、EMBASE 和 Cochrane Library 数据库，检索时间截至 2021 年 5 月 31 日。纳入了包括接受彩色血流多普勒采样以突出闪烁伪影和计算机断层扫描的尿路结石患者的研究。采用双变量模型进行诊断试验荟萃分析。我们使用汇总受试者工作特征曲线来总结整体诊断性能。计算了加权敏感度、特异性、阳性似然比和阴性似然比。
结果
系统评价和荟萃分析共纳入 16 项研究，涉及 4572 例患者。加权敏感度为 0.86（95%置信区间 0.72-0.94），特异性为 0.92（95%置信区间 0.75-0.98），阳性似然比为 11.3，阴性似然比为 0.2，诊断优势比为 75.5。
结论
多普勒闪烁伪影对尿路结石的诊断具有良好的诊断价值，应作为尿路结石诊断的辅助工具。
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