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近期感染 SARS-CoV-2 后的膜性肾病。

Membranous nephropathy after a recent SARS-CoV-2 infection.

机构信息

Nephrology Department, Centro Hospitalar de Lisboa Ocidental EPE Hospital de Santa Cruz, Carnaxide, Lisboa, Portugal

Pathology Department, Centro Hospitalar de Lisboa Ocidental EPE Hospital de Egas Moniz, Lisboa, Portugal.

出版信息

BMJ Case Rep. 2023 Jan 27;16(1):e252468. doi: 10.1136/bcr-2022-252468.

Abstract

SARS-CoV-2 infections can induce kidney injury and glomerulopathy, with the most common pathology findings being acute tubular injury and collapsing glomerulopathy.Here we describe a rare case of membranous nephropathy in a man in his late 70s presented with nephrotic syndrome and rapidly progressive kidney dysfunction 1 month after SARS-CoV-2 infection. Phospholipase A2 receptor antibodies were positive. He was treated with rituximab, with proteinuria control. We review the cases reported in the literature.

摘要

SARS-CoV-2 感染可引起肾损伤和肾小球病,最常见的病理表现为急性肾小管损伤和塌陷性肾小球病。在此,我们描述了一例罕见的 70 多岁男性病例,该患者在 SARS-CoV-2 感染后 1 个月出现肾病综合征和快速进行性肾功能衰竭。该患者的磷脂酶 A2 受体抗体阳性。他接受了利妥昔单抗治疗,蛋白尿得到控制。我们对文献中报道的病例进行了回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/178f/9884916/a842a3540ed2/bcr-2022-252468f01.jpg

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