Fagundes Nathalia Carolina Fernandes, Minervini Giuseppe, Furio Alonso Berta, Nucci Ludovica, Grassia Vincenzo, d'Apuzzo Fabrizia, Puigdollers Andreu, Perillo Letizia, Flores-Mir Carlos
School of Dentistry, Faculty of Medicine and Dentistry, College of Health Sciences, University of Alberta, Edmonton, Alberta, Canada.
Multidisciplinary Department of Medical-Surgical and Dental Specialties, Orthodontic Program, University of Campania Luigi Vanvitelli, Naples, Italy.
J Evid Based Dent Pract. 2023 Jan;23(1S):101786. doi: 10.1016/j.jebdp.2022.101786. Epub 2022 Oct 17.
This scoping review aims to describe dental treatment-related patient-reported outcomes (dPROs) while using oral appliances (OAs) to manage obstructive sleep apnea (OSA) in children and adults.
Available literature that assessed dPROs in children and adults with OSA managed through OAs. Any clinical studies were included without restrictions of year or country. The results were analyzed and reported using narrative text and tables accompanying a descriptive summary.
The searches identified 1718 citations, and of these, forty-five studies were finally included. A total of 3498 adults were included in all 42 primary studies included in this review, in which all the studies presented adults as participants. The dPROs assessed were quality of life (QoL), reported side effects after OA usage, patient satisfaction, and experience with treatment, and subjective perception of occlusal changes after treatment.
This scoping review suggests that dPROs are mostly investigated as a secondary outcome from major studies exploring the effects of OAs on OSA severity, and often, dPROs are not well discussed or displayed on their report. As no risk of bias or certainty level assessment was completed, findings need to be carefully considered. Although in general terms management with OAs among adults with OSA does not seem to be uncomfortable or causing major problems to their lives, some mild discomfort and endured occlusal disturbances was reported in some studies. QoL seems to improve but consistent agreement was elusive. Data does not include experiences among those that dropped OA use. No data seems to exist about dPROs in children.
本综述旨在描述在儿童和成人使用口腔矫治器(OA)治疗阻塞性睡眠呼吸暂停(OSA)期间与牙科治疗相关的患者报告结局(dPROs)。
检索评估通过OA治疗的儿童和成人OSA患者dPROs的现有文献。纳入任何临床研究,不受年份或国家限制。使用叙述性文本和描述性总结表格对结果进行分析和报告。
检索到1718篇文献,最终纳入45项研究。本综述纳入的所有42项主要研究共纳入3498名成人,所有研究均以成人作为参与者。评估的dPROs包括生活质量(QoL)、使用OA后的副作用报告、患者满意度、治疗体验以及治疗后对咬合变化的主观感受。
本综述表明,dPROs大多作为探索OA对OSA严重程度影响的主要研究的次要结局进行调查,而且在其报告中,dPROs往往没有得到充分讨论或展示。由于未完成偏倚风险或确定性水平评估,研究结果需谨慎考虑。虽然总体而言,OSA成人患者使用OA治疗似乎不会带来不适或对其生活造成重大问题,但一些研究报告了一些轻微不适和持续的咬合紊乱。生活质量似乎有所改善,但尚未达成一致意见。数据不包括停止使用OA者的经历。似乎没有关于儿童dPROs的数据。