Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA 94305, USA.
Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Stanford University, 300 Pasteur Drive, H2200, Stanford, CA 94305, USA.
PET Clin. 2023 Apr;18(2):259-266. doi: 10.1016/j.cpet.2022.11.008. Epub 2023 Jan 25.
Imaging plays a critical role in the diagnosis and management of neuroendocrine tumors (NETs). The initial workup of the primary tumor, including its characterization, local and distant staging, defines subsequent treatment decisions. Functional imaging using hybrid systems, such as PET combined with computed tomography, has become the gold standard. As NETs majorly arise from the gastrointestinal system and metastasize primarily to the liver, simultaneous PET and MR imaging with its high soft tissue contrast might be a valuable clinical one-stop-shop whole-body imaging tool. This review presents the current status and challenges of PET/MR imaging for diagnosis of NETs.
影像学在神经内分泌肿瘤(NET)的诊断和治疗中起着关键作用。初始的原发性肿瘤检查,包括其特征、局部和远处分期,决定了后续的治疗决策。使用混合系统(如与计算机断层扫描相结合的 PET)进行功能成像已成为金标准。由于 NET 主要源自胃肠道系统,主要转移到肝脏,因此具有高软组织对比度的同时 PET 和 MR 成像可能是一种有价值的临床一站式全身成像工具。本综述介绍了 PET/MR 成像在 NET 诊断中的现状和挑战。