乳腺癌女性的认知功能：癌症治疗认知功能工具阿拉伯语版的心理测量特性。
Cognitive functioning in women with breast cancer: psychometric properties of the Arabic version of the Functional Assessment of Cancer Therapy-Cognitive Function Tool.
机构信息
Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
INSPECT-LB (Institut National de Santé Publique Epidémiologie Clinique et Toxicologie-Liban), Beirut, Lebanon.
出版信息
Health Qual Life Outcomes. 2023 Jan 28;21(1):9. doi: 10.1186/s12955-023-02095-0.
BACKGROUND
The Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) evaluates perceived cognitive functioning and their impact on quality of life. This study was designed to evaluate the factors associated with cognitive functioning in a sample of women with breast cancer (BC) in Lebanon. We also sought to explore the psychometric properties of the FACT-Cog Arabic version.
METHODS
A cross-sectional study was carried out between March and August 2020 among women with BC. Socio-demographic and clinical characteristics were collected. In addition, patients were asked to complete the FACT-Cog Arabic version as well as the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30, the Patient Health Questionnaire (PHQ-9), and the Generalized Anxiety Disorder (GAD-7). The internal consistency of the FACT-Cog tool was evaluated using Cronbach's alpha. Content, convergent, and known group validity of the FACT-Cog Arabic version were also evaluated. All statistical analyses were performed using SPSS version 23.0.
RESULTS
A sample of 134 women with BC was collected. Internal consistencies of the FACT-cog total scale and its subscales were high (Cronbach's α between 0.83 and 0.95). The convergent validity of the FACT-Cog Arabic version was supported by the positive correlation with the EORTC-cognitive functioning subscale. Moreover, negative correlations were found between FACT-Cog scale and fatigue, pain, anxiety, as well as depression. Known-group validity was supported by the statistically significant mean differences of the FACT-Cog total scale between patients in early (I &II) and late (III & IV) BC stages. Unmarried BC patients as well as those having higher depressive symptoms and a lower quality of life were found to be at higher risk of cognitive impairment.
CONCLUSION
The FACT-Cog Lebanese Arabic version is a valid and reliable tool for assessing perceived cognitive functioning in BC women. Higher level of depression and impaired quality of life were associated with a decline in cognitive functioning.
背景
癌症治疗功能评估-认知功能（FACT-Cog）评估认知功能的感知及其对生活质量的影响。本研究旨在评估黎巴嫩乳腺癌（BC）患者样本中与认知功能相关的因素。我们还试图探索 FACT-Cog 阿拉伯语版本的心理测量特性。
方法
2020 年 3 月至 8 月期间进行了一项横断面研究，研究对象为 BC 女性。收集了社会人口统计学和临床特征。此外，患者还被要求完成 FACT-Cog 阿拉伯语版本，以及欧洲癌症研究与治疗组织生活质量核心问卷 30 项、患者健康问卷（PHQ-9）和广泛性焦虑障碍（GAD-7）。使用 Cronbach's alpha 评估 FACT-Cog 工具的内部一致性。还评估了 FACT-Cog 阿拉伯语版本的内容、收敛和已知组有效性。所有统计分析均使用 SPSS 版本 23.0 进行。
结果
共收集了 134 名 BC 女性的样本。FACT-cog 总量表及其分量表的内部一致性较高（Cronbach's α 在 0.83 到 0.95 之间）。FACT-Cog 阿拉伯语版本的收敛有效性得到了支持，与 EORTC 认知功能分量表呈正相关。此外，FACT-Cog 量表与疲劳、疼痛、焦虑以及抑郁呈负相关。已知组有效性得到了支持，FACT-Cog 总量表在早期（I 和 II）和晚期（III 和 IV）BC 阶段的患者之间存在统计学上显著的平均差异。未婚 BC 患者以及那些具有更高抑郁症状和更低生活质量的患者被发现认知功能障碍的风险更高。
结论
FACT-Cog 黎巴嫩阿拉伯语版本是一种有效的、可靠的工具，用于评估 BC 女性的认知功能。较高的抑郁水平和较差的生活质量与认知功能下降有关。
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