Zarabi C M, Litton N
University of Missouri, Kansas City School of Medicine.
Oncology. 1987;44(5):287-91. doi: 10.1159/000226497.
Light microscopy of sections from the paraaortic and pelvic lymph nodes of a patient revealed micrometastases with sinus pattern. The diagnosis of metastatic rhabdomyosarcoma was confirmed ultrastructurally by demonstration of actin filaments and Z bands. To our knowledge occult metastases of rhabdomyosarcoma with purely sinus pattern have not been reported previously and diagnosis might be difficult to establish clinically or pathologically. However, recognition of the lymph node involvement changes the clinical staging and therapeutic regimen of this disease. Therefore, rhabdomyosarcoma should be included in the differential diagnosis of lymphadenopathies with sinus pattern. The disorders causing sinus pattern in lymph nodes are briefly reviewed.
一名患者主动脉旁和盆腔淋巴结切片的光学显微镜检查显示有呈窦状模式的微转移灶。通过肌动蛋白丝和Z带的显示，超微结构证实为转移性横纹肌肉瘤。据我们所知，此前尚未报道过具有纯窦状模式的横纹肌肉瘤隐匿转移，临床或病理诊断可能难以确立。然而，认识到淋巴结受累会改变该疾病的临床分期和治疗方案。因此，横纹肌肉瘤应纳入具有窦状模式淋巴结病的鉴别诊断中。本文简要综述了导致淋巴结出现窦状模式的疾病。
