[Research progress of Molecular diagnostic technique in Venous Thromboembolism].
作者信息
Cai Y H, Deng J, Hu Y
机构信息
Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
出版信息
Zhonghua Xue Ye Xue Za Zhi. 2022 Nov 14;43(11):964-968. doi: 10.3760/cma.j.issn.0253-2727.2022.11.015.
Abstract
摘要
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Genome sequencing unveils a regulatory landscape of platelet reactivity.基因组测序揭示了血小板反应性的调控图谱。
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Targeted next-generation sequencing reveals novel and known variants of thrombophilia associated genes in Saudi patients with venous thromboembolism.靶向新一代测序揭示沙特静脉血栓栓塞患者中血栓形成倾向相关基因的新变异和已知变异。
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Single- and Multimarker Genome-Wide Scans Evidence Novel Genetic Risk Modifiers for Venous Thromboembolism.单基因和多基因全基因组扫描为静脉血栓栓塞提供新的遗传风险修饰因子。
Thromb Haemost. 2021 Sep;121(9):1169-1180. doi: 10.1055/s-0041-1723988. Epub 2021 Feb 16.
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Expressions and relationship of Krüppel-like factor 15 and endothelial nitric oxide synthase in experimental deep venous thrombosis.实验性深静脉血栓形成中Krüppel样因子15与内皮型一氧化氮合酶的表达及关系
Ann Transl Med. 2020 Sep;8(17):1090. doi: 10.21037/atm-20-5828.
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Hum Mutat. 2020 Nov;41(11):1848-1865. doi: 10.1002/humu.24114. Epub 2020 Oct 8.
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Pathogenic and likely pathogenic variants in at least five genes account for approximately 3% of mild isolated nonsyndromic thrombocytopenia.至少有五个基因的致病性和可能致病性变异约占轻度孤立性无综合征血小板减少症的 3%。
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J Thromb Haemost. 2020 Aug;18(8):1839-1845. doi: 10.1111/jth.14945.
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