Department of Health Policy and Organization, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Research, Care and Treatment Programme, Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Value Health Reg Issues. 2023 Mar;34:125-132. doi: 10.1016/j.vhri.2022.11.003. Epub 2023 Jan 27.
Home-based couples HIV testing and counseling and HIV self-testing (HIVST) for pregnant women can promote HIV status disclosure and male partner testing; however, cost data are lacking. We examined a home-based couples intervention (HBCI) and HIVST intervention costs per couple (unit cost) during pregnancy and postpartum in Kenya.
This randomized controlled trial is comparing HBCI and HIVST for couples among pregnant women attending antenatal care clinics in two counties in southwestern Kenya. We used micro-costing to estimate the unit cost per couple receiving the intervention as the total of direct and indirect costs for each study arm in 2019 US$. We used a one-month window to conduct a time and motion study to determine personnel effort and resources. We then compared the unit cost by arm, identified key cost drivers, and conducted sensitivity analyses for cost uncertainties.
At base-case, the unit cost was $129.01 and $41.99, respectively, for HBCI and HIVST. Personnel comprised half of the unit cost for both arms. Staff spent more time on activities related to participant engagement in HBCI (accounting for 6.4% of the unit cost) than in HIVST (2.3%). Staff training was another key cost driver in HBCI (20.1% of the unit cost compared to 12.5% in HIVST). Sensitivity analyses revealed that the unit cost ranges were $104.64-$154.54 for HBCI and $30.49-$56.59 for HIVST.
Our findings may guide spending decisions for future HIV prevention and treatment programs for pregnant couples in resource-limited settings such as Kenya.
针对孕妇的家庭为基础的伴侣 HIV 检测和咨询以及 HIV 自检(HIVST)可以促进 HIV 状况的披露和男性伴侣检测;然而,缺乏成本数据。我们检查了肯尼亚两个县的产前保健诊所中针对孕妇的家庭为基础的伴侣干预(HBCI)和 HIVST 干预的成本(单位成本)。
本随机对照试验正在比较 HBCI 和 HIVST 在肯尼亚西南部两个县的产前保健诊所中针对孕妇的伴侣的效果。我们使用微观成本法来估计每个研究组中接受干预的每对夫妇的单位成本,即每个研究臂的直接和间接成本总和,以 2019 年的美元计算。我们使用一个月的窗口期来进行时间和动作研究,以确定人员的努力和资源。然后,我们按组比较了单位成本,确定了关键成本驱动因素,并对成本不确定性进行了敏感性分析。
在基线情况下,HBCI 和 HIVST 的单位成本分别为 129.01 美元和 41.99 美元。人员构成了两个组的单位成本的一半。工作人员在 HBCI 中与参与者参与相关的活动上花费的时间更多(占单位成本的 6.4%),而在 HIVST 中则较少(2.3%)。员工培训是 HBCI 的另一个关键成本驱动因素(占单位成本的 20.1%,而 HIVST 为 12.5%)。敏感性分析显示,HBCI 的单位成本范围为 104.64-154.54 美元,HIVST 的单位成本范围为 30.49-56.59 美元。
我们的研究结果可能为资源有限的肯尼亚等国家的未来针对孕妇的夫妇的艾滋病毒预防和治疗方案的支出决策提供指导。