Nutrition Services, Alberta Health Services, Edmonton, Alberta, Canada; Department of Agricultural, Food and Nutritional Sciences, 4-002G Li Ka Shing Centre for Health Innovation, University of Alberta, Edmonton, Alberta, Canada.
Nutrition Services, Alberta Health Services, Edmonton, Alberta, Canada.
Nutr Metab Cardiovasc Dis. 2023 Mar;33(3):610-619. doi: 10.1016/j.numecd.2022.12.016. Epub 2022 Dec 23.
Plant proteins may be restricted on low potassium/phosphorus diets. The primary objective was to investigate the impact of protein source on serum potassium and phosphate levels in adults with stage 4-5 chronic kidney disease (CKD), including hemodialysis (HD).
Using a cross-sectional design, 24-h recalls or food frequency questionnaires were used to assess dietary intake. Serum values were obtained from medical records. Quartiles (Q1-4) of plant:animal protein serving ratios was considered to investigate outcomes, with Q1 having high animal and low plant serving intake and those in Q4 having high plant and low animal servings. 216 participants were enrolled, 135 on HD and 81 stage 4/5 CKD. For both HD and CKD, there was no difference in either serum potassium or phosphate levels between those in Q4 consuming high plant:animal vs Q1 low plant:animal (for HD: potassium 4.6 mmol/L vs 4.6 mmol/L; phosphate 1.8 mmol/L vs 1.6 mmol/L, respectively; for CKD: potassium 4.7 mmol/L vs 4.6 mmol/L; phosphate 1.4 mmol/L vs 1.4 mmol/L; all p > 0.05). Those in Q4 consuming high plant:animal consumed 7.5 g (62%) more fibre than those in Q1 (low plant:animal). For diet quality, Q4 (high plant:animal) had a 12.8 point (24%) higher healthy eating index score than Q1 (low plant:animal). There was no relationship between plant:animal and serum albumin or hospital admissions (all p > 0.05).
Consumption of higher proportions of plant protein was not associated with higher serum potassium or phosphate levels but was associated with higher fibre and diet quality.
植物蛋白可能在低钾/低磷饮食中受到限制。主要目的是研究蛋白质来源对 4-5 期慢性肾脏病（CKD）成人（包括血液透析（HD）患者）血清钾和磷水平的影响。
使用横断面设计，通过 24 小时回顾或食物频率问卷评估饮食摄入量。从病历中获取血清值。植物：动物蛋白质份数比的四分位数（Q1-4）被认为是调查结果的指标，其中 Q1 具有高动物和低植物的摄入份数，而 Q4 具有高植物和低动物的摄入份数。共纳入 216 名参与者，其中 135 名在接受 HD 治疗，81 名处于 4/5 期 CKD 阶段。对于 HD 和 CKD 患者，Q4 组（高植物：动物）与 Q1 组（低植物：动物）消耗高植物：动物与低植物：动物的血清钾或磷水平均无差异（对于 HD：钾 4.6mmol/L 与 4.6mmol/L；磷 1.8mmol/L 与 1.6mmol/L，分别；对于 CKD：钾 4.7mmol/L 与 4.6mmol/L；磷 1.4mmol/L 与 1.4mmol/L；所有 p>0.05）。Q4 组（高植物：动物）消耗的纤维比 Q1 组（低植物：动物）多 7.5g（62%）。对于饮食质量，Q4（高植物：动物）的健康饮食指数得分比 Q1（低植物：动物）高 12.8 分（24%）。植物：动物与血清白蛋白或住院之间没有关系（所有 p>0.05）。
消耗较高比例的植物蛋白与较高的血清钾或磷水平无关，但与较高的纤维和饮食质量有关。
