State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University (NPU) and Shaanxi Joint Laboratory of Graphene, Xi'an, 710072, P. R. China.
Key Laboratory of Micro/Nano Systems for Aerospace (Ministry of Education), Shaanxi Province Key Laboratory of Micro and Nano Electro-Mechanical Systems, School of Mechanical Engineering, NPU, Xi'an, 710072, P. R. China.
Small. 2023 Apr;19(16):e2206868. doi: 10.1002/smll.202206868. Epub 2023 Jan 29.
Wearable glucose sensors are of great significance and highly required in mobile health monitoring and management but suffering from limited long-term stability and wearable adaptability. Here a simultaneous component and structure engineering strategy is presented, which involves Pt with abundant Ni to achieve three-dimensional, dual-structural Pt-Ni hydrogels with interconnected networks of PtNi nanowires and Ni(OH) nanosheets, showing prominent electrocatalytic activity and stability in glucose oxidation under neutral condition. Specifically, the PtNi dual hydrogels shows 2.0 and 270.6 times' activity in the glucose electro-oxidation as much as the pure Pt and Ni hydrogels. Thanks to the high activity, structural stability, good flexibility, and self-healing property, the PtNi dual gel-based non-enzymatic glucose sensing chip is endowed with high performance. It features a high sensitivity, an excellent selectivity and flexibility, and particularly an outstanding long-term stability over 2 months. Together with a pH sensor and a wireless circuit, an accurate, real-time, and remote monitoring of sweat glucose is achieved. This facile design of novel dual-structural metallic hydrogels sheds light to rationally develop new functional materials for high-performance wearable biosensors.
可穿戴葡萄糖传感器在移动健康监测和管理中具有重要意义和高度需求，但存在长期稳定性和可穿戴适应性有限的问题。本文提出了一种同时的组成和结构工程策略，涉及富含 Ni 的 Pt 以实现具有 PtNi 纳米线和 Ni(OH)纳米片相互连接网络的三维、双结构 Pt-Ni 水凝胶，在中性条件下葡萄糖氧化中表现出突出的电催化活性和稳定性。具体而言，PtNi 双水凝胶在葡萄糖电氧化中的活性是纯 Pt 和 Ni 水凝胶的 2.0 和 270.6 倍。由于高活性、结构稳定性、良好的柔韧性和自修复性，基于 PtNi 双凝胶的非酶葡萄糖传感芯片具有高性能。它具有高灵敏度、优异的选择性和柔韧性，特别是在 2 个月以上的时间内具有出色的长期稳定性。与 pH 传感器和无线电路相结合，实现了对汗液葡萄糖的准确、实时和远程监测。这种新型双结构金属水凝胶的简便设计为高性能可穿戴生物传感器的合理开发新型功能材料提供了思路。
