Selective degradation of the p53-R175H oncogenic hotspot mutant by an RNA aptamer-based PROTAC.
作者信息
Kong Lingping, Meng Fanlu, Wu Sijin, Zhou Ping, Ge Ruixin, Liu Min, Zhang Linlin, Zhou Jun, Zhong Diansheng, Xie Songbo
机构信息
Department of Medical Oncology, Tianjin Medical University General Hospital, Tianjin, China.
Laboratory of Molecular Modeling and Design, State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
出版信息
Clin Transl Med. 2023 Feb;13(2):e1191. doi: 10.1002/ctm2.1191.
Abstract
摘要
Zotero 插件