Suppr超能文献

病例报告:一名年轻男性患者出现血管痉挛诱发的心肌梗死并伴有ST段抬高的罕见表现。

Case report: A rare manifestation of vasospasm induced myocardial infarction with ST-segment elevation in a young male patient.

作者信息

Diečkus Laurynas, Rodevič Greta, Baranauskas Arvydas, Davidavičius Giedrius, Budrys Povilas

机构信息

Clinic of Cardiac and Vascular Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Center of Internal Diseases, Vilnius University Hospital Santaros Clinics, Vilnius, Lithuania.

出版信息

Front Cardiovasc Med. 2023 Jan 12;9:1017107. doi: 10.3389/fcvm.2022.1017107. eCollection 2022.

Abstract

BACKGROUND

Minority of acute myocardial infarctions (MI) are caused by a non-atherosclerotic occlusion of the coronary artery. We present a case report, where MI with ST-segment elevation was provoked by a vasospasm, which is a rare aetiological finding.

CASE PRESENTATION

27-year-old male patient presented to the emergency department because of a sudden onset chest pain radiating to the left arm. The patient underwent percutaneous coronary intervention (PCI) to the right coronary artery (RCA) 3 months ago due to inferior wall MI, however, chest pain episodes kept on recurring at night throughout the whole period after the intervention. During current admission, initial electrocardiogram (ECG) demonstrated ST-segment elevation in leads II, III and aVF. Coronary angiogram revealed diffuse severe narrowing of the right coronary artery, which was relieved with intracoronary administration of nitrates and verapamil. After coronary angiogram patient was given oral long-acting nitrates and verapamil, however, during the following days nocturnal chest pain episodes reoccurred. It was decided to swap verapamil to diltiazem, which led to complete cessation of angina episodes. The patient was discharged in stable condition and symptom free. It was suspected that the first MI was of vasospastic origin, which likely led to unnecessary stenting.

CONCLUSIONS

This clinical case has demonstrated the challenges clinician could face in order to correctly diagnose vasospasm-induced MI because of its rare occurrence and highly variable presentation. We strongly suggest using intracoronary nitroglycerine during coronary angiography as a standard practice to avoid a potential diagnostic error and unnecessary stenting. Although, in some cases the reason behind coronary artery spasm (CAS) remains unclear, medical treatment can be very effective for CAS prevention.

摘要

背景

少数急性心肌梗死(MI)是由冠状动脉非动脉粥样硬化性闭塞引起的。我们报告一例病例,ST段抬高型心肌梗死由血管痉挛诱发,这是一种罕见的病因。

病例介绍

一名27岁男性患者因突发胸痛放射至左臂就诊于急诊科。该患者3个月前因下壁心肌梗死接受了右冠状动脉(RCA)的经皮冠状动脉介入治疗(PCI),然而,介入治疗后的整个期间夜间胸痛发作持续反复出现。在本次入院期间,初始心电图(ECG)显示II、III和aVF导联ST段抬高。冠状动脉造影显示右冠状动脉弥漫性严重狭窄,冠状动脉内给予硝酸酯类药物和维拉帕米后狭窄缓解。冠状动脉造影后患者服用口服长效硝酸酯类药物和维拉帕米,然而,在接下来的几天里夜间胸痛发作再次出现。决定将维拉帕米换为地尔硫䓬,这导致心绞痛发作完全停止。患者出院时病情稳定且无症状。怀疑首次心肌梗死为血管痉挛性起源,这可能导致了不必要的支架置入。

结论

该临床病例表明,由于血管痉挛性心肌梗死发生率低且表现高度多变,临床医生在正确诊断时可能面临挑战。我们强烈建议在冠状动脉造影期间常规使用冠状动脉内硝酸甘油,以避免潜在的诊断错误和不必要的支架置入。虽然在某些情况下冠状动脉痉挛(CAS)的原因仍不清楚,但药物治疗对预防CAS可能非常有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f73/9877510/1508d5f4c3a0/fcvm-09-1017107-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验