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酗酒者的全血细胞减少和叶酸缺乏

Pancytopenia and folate deficiency in alcoholics.

作者信息

Weston C F, Hall M J

机构信息

Department of Medicine, Bristol Royal Infirmary, UK.

出版信息

Postgrad Med J. 1987 Feb;63(736):117-20. doi: 10.1136/pgmj.63.736.117.

Abstract

Three alcoholic patients are reported who presented with pancytopenia and macrocytosis due to acute folate deficiency. While folate deficiency is a common finding in alcohol abusers due to abnormalities in diet, intestinal absorption, internal metabolism and excretion, this life-threatening complication has not been well documented.

摘要

报告了3例酒精性患者,他们因急性叶酸缺乏出现全血细胞减少和大细胞性贫血。虽然由于饮食、肠道吸收、体内代谢和排泄异常,叶酸缺乏在酗酒者中很常见,但这种危及生命的并发症尚未得到充分记录。

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Pancytopenia and folate deficiency in alcoholics.酗酒者的全血细胞减少和叶酸缺乏
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本文引用的文献

1
Acute folate deficiency during peritoneal dialysis.
Br Med J. 1980 Dec 13;281(6255):1602. doi: 10.1136/bmj.281.6255.1602.
2
The effects of alcohol on folate metabolism.酒精对叶酸代谢的影响。
Annu Rev Med. 1982;33:345-54. doi: 10.1146/annurev.me.33.020182.002021.
3
Role of ethanol metabolism in the alcohol-induced increase in urinary folate excretion in rats.
Biochem Pharmacol. 1983 Sep 1;32(17):2549-55. doi: 10.1016/0006-2952(83)90017-5.
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The evolution of anemia in alcoholic patients.酒精性患者贫血的演变
Am J Med. 1971 Feb;50(2):218-32. doi: 10.1016/0002-9343(71)90151-3.
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Variations in the hematologic and medical status of alcoholics.
Am J Med Sci. 1972 Jan;263(1):35-42. doi: 10.1097/00000441-197201000-00006.
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Folic acid deficiency during intensive therapy.强化治疗期间的叶酸缺乏
Br Med J. 1975 Oct 18;4(5989):145. doi: 10.1136/bmj.4.5989.145.
10

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