酗酒者的全血细胞减少和叶酸缺乏
Pancytopenia and folate deficiency in alcoholics.
作者信息
Weston C F, Hall M J
机构信息
Department of Medicine, Bristol Royal Infirmary, UK.
出版信息
Postgrad Med J. 1987 Feb;63(736):117-20. doi: 10.1136/pgmj.63.736.117.
Abstract
Three alcoholic patients are reported who presented with pancytopenia and macrocytosis due to acute folate deficiency. While folate deficiency is a common finding in alcohol abusers due to abnormalities in diet, intestinal absorption, internal metabolism and excretion, this life-threatening complication has not been well documented.
摘要
报告了3例酒精性患者，他们因急性叶酸缺乏出现全血细胞减少和大细胞性贫血。虽然由于饮食、肠道吸收、体内代谢和排泄异常，叶酸缺乏在酗酒者中很常见，但这种危及生命的并发症尚未得到充分记录。
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本文引用的文献
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The effects of alcohol on folate metabolism.酒精对叶酸代谢的影响。
Annu Rev Med. 1982;33:345-54. doi: 10.1146/annurev.me.33.020182.002021.
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Role of ethanol metabolism in the alcohol-induced increase in urinary folate excretion in rats.乙醇代谢在酒精诱导的大鼠尿中叶酸排泄增加中的作用。
Biochem Pharmacol. 1983 Sep 1;32(17):2549-55. doi: 10.1016/0006-2952(83)90017-5.
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Reversible megaloblastic and sideroblastic marrow abnormalities in alcoholic patients.酒精性患者中可逆性巨幼细胞性和环形铁粒幼细胞性骨髓异常
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The evolution of anemia in alcoholic patients.酒精性患者贫血的演变
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Variations in the hematologic and medical status of alcoholics.酗酒者血液学和医学状况的变化。
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Intestinal malabsorption in folate-deficient alcoholics.叶酸缺乏的酗酒者的肠道吸收不良。
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