Characteristics of different types of : New evidence from non-amplified white light endoscopy.

BACKGROUND

Different types of were analyzed to determine their infection characteristics using serology, pathology, and non-magnification white light endoscopy combined with the Kimura-Takemoto classification, and the regular arrangement of collecting venules (RAC) as well.

MATERIALS AND METHODS

A retrospective analysis of 685 inpatients who have completed the C-urea breath test, the antibody typing classification, the serum gastric function tests (PGI/PGII/G-17), the endoscope detection, and the pathological examinations.

RESULTS

The levels of PGI, PGII, and G-17 were in descending order from the type I infection group to the type II infection group than the control group ( = 14.31; 26.23; 9.12,  < 0.01). Using the Kimura-Takemoto classification, there were significant differences among the three groups of different degrees of atrophy ( =29.81; 482.78; 292.5, 0.01). Based on the characteristics of RAC, the infection rates were in descending order from the type I infection group to the type II infection group than the control group ( = 200.39; 174.72; 143.51,  < 0.01). The type I infection group had higher grades than those of the type II infection group in the OLGA and OLGIM staging systems, while the differences are statistically significant only in the OLGA staging system ( =10.63,  < 0.05).

CONCLUSION

With the aid of non-amplified white light endoscopy, we found new evidence of type I infection accelerating the progression of gastric mucosal atrophy through the degree of atrophy and the range of infection, whereas type II infection has a low ability of migration and atrophy progression. Individual virulence factor-based eradication therapy may be a better choice in future.