Lei Jin, Li Yu, Wan Xueyan, Wang Junwen, You Chao, Zhao Kai, Niu Hongquan
Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Front Oncol. 2023 Jan 13;12:1097155. doi: 10.3389/fonc.2022.1097155. eCollection 2022.
Schwannomas of the trochlear nerve with the absence of systemic neurofibromatosis are considerably uncommon, especially complicated by intra-tumoral hemorrhage. Due to the lack of typical clinical manifestations and imaging findings, a definite diagnosis of trochlear schwannomas before surgery is particularly difficult.
We report the case of a 64-year-old female patient who presented with a unilaterally intermittent headache of 2-month duration and without a remarkable neurological deficit at admission. Imaging studies revealed a well-demarcated cystic-solid lesion with mixed signals beside the brainstem and suprasellar cisterna. The patient underwent a surgical operation with total resection of the tumor by a subtemporal surgical approach. The tumor was intraoperatively found to originate from the trochlear nerve and was pathologically confirmed as a hemorrhagic schwannoma with cystic degeneration.
We describe this case in detail and conduct a concomitant survey of the literature, summarizing the clinical presentations, radiological features, surgical treatment, and the possible mechanisms of hemorrhage in relevance to trochlear nerve schwannoma.
无系统性神经纤维瘤病的滑车神经鞘瘤相当罕见,尤其是合并瘤内出血时。由于缺乏典型的临床表现和影像学表现,术前明确诊断滑车神经鞘瘤尤为困难。
我们报告一例64岁女性患者,该患者出现单侧间歇性头痛2个月,入院时无明显神经功能缺损。影像学检查显示脑干和鞍上池旁有一个边界清晰的囊实性病变,信号混杂。患者接受了颞下手术入路全切除肿瘤的手术。术中发现肿瘤起源于滑车神经,病理证实为囊性变的出血性神经鞘瘤。
我们详细描述了该病例,并对文献进行了综述,总结了滑车神经鞘瘤的临床表现、影像学特征、手术治疗以及出血的可能机制。