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双猪尾管引流术治疗巨大多房性化脓性肝脓肿

Double pigtail tube drainage for large multiloculated pyogenic liver abscesses.

作者信息

JinHua Cui, YaMan Liu, Jian Li

机构信息

Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical College, Chengde, China.

Department of Gynaecology, Affiliated Hospital of Chengde Medical College, Chengde, China.

出版信息

Front Surg. 2023 Jan 12;9:1106348. doi: 10.3389/fsurg.2022.1106348. eCollection 2022.

DOI:10.3389/fsurg.2022.1106348
PMID:36713673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9877412/
Abstract

BACKGROUND

This study aims to investigate the efficacy and safety of double pigtail tube drainage compared with single pigtail tube drainage for the treatment of multiloculated pyogenic liver abscesses greater than 5 cm.

PATIENTS AND METHODS

This study retrospectively analyzed patients with pyogenic liver abscess admitted in the Affiliated Hospital of Chengde Medical College between May 2013 and May 2021. Patients with pyogenic liver abscess more than 5 cm in size, who underwent drainage of the abscess with either double pigtail or single pigtail tube, were included.

RESULTS

A total of 97 patients with pyogenic liver abscesses larger than 5 cm were studied. These included 34 patients with double pigtail tube drainage and 63 patients with single pigtail tube drainage. The postoperative hospital stay (13.39 ± 4.21 days vs. 15.67 ± 7.50 days;  = 0.045), and time for removal of the catheter (17.23 ± 3.70 days vs. 24.11 ± 5.83 days;  = 0.038) were lower in the double pigtail tube group compared with the single pigtail tube group. The rate of reduction, in three days, of c-reactive protein levels was 26.61 ± 14.11 mg/L/day in the double pigtail tube group vs. 20.06 ± 11.74 mg/L/day in the single pigtail tube group ( = 0.025). The diameter of the abscess cavity at discharge was 3.1 ± 0.07 cm in the double pigtail tube group as compared with 3.7 ± 0.6 cm in the single pigtail tube group ( = 0.047). There was no bleeding in any of the patients despite abnormal coagulation profiles. There was no recurrence of abscess within six months of discharge and no death in the double pigtail tube group. Conclusion: Double pigtail tube drainage treatment in multiloculated pyogenic liver abscesses greater than 5 cm in size, is safe and effective.

摘要

背景

本研究旨在探讨双猪尾管引流与单猪尾管引流治疗直径大于5 cm的多房性化脓性肝脓肿的疗效和安全性。

患者与方法

本研究回顾性分析了2013年5月至2021年5月在承德医学院附属医院收治的化脓性肝脓肿患者。纳入了脓肿直径大于5 cm、采用双猪尾管或单猪尾管进行脓肿引流的化脓性肝脓肿患者。

结果

共研究了97例直径大于5 cm的化脓性肝脓肿患者。其中双猪尾管引流组34例,单猪尾管引流组63例。双猪尾管组术后住院时间(13.39±4.21天 vs. 15.67±7.50天;P=0.045)和拔管时间(17.23±3.70天 vs. 24.11±5.83天;P=0.038)均低于单猪尾管组。双猪尾管组c反应蛋白水平三天内的下降速率为26.61±14.11 mg/L/天,单猪尾管组为20.06±11.74 mg/L/天(P=0.025)。双猪尾管组出院时脓肿腔直径为3.1±0.07 cm,单猪尾管组为3.7±0.6 cm(P=0.047)。尽管凝血指标异常,但所有患者均未发生出血。双猪尾管组出院后六个月内无脓肿复发,无死亡病例。结论:双猪尾管引流治疗直径大于5 cm的多房性化脓性肝脓肿安全有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/9877412/a681df9ca685/fsurg-09-1106348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/9877412/a2f9afec782b/fsurg-09-1106348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/9877412/a681df9ca685/fsurg-09-1106348-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/9877412/a2f9afec782b/fsurg-09-1106348-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c75/9877412/a681df9ca685/fsurg-09-1106348-g002.jpg

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Malays J Med Sci. 2022 Oct;29(5):59-73. doi: 10.21315/mjms2022.29.5.7. Epub 2022 Oct 28.
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Infect Drug Resist. 2023 Jun 22;16:4013-4023. doi: 10.2147/IDR.S416860. eCollection 2023.
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