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Vet Ophthalmol. 2021 Jul;24(4):346-353. doi: 10.1111/vop.12892. Epub 2021 May 6.
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Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysis.术后继续使用抗生素预防对手术部位感染发生率的影响:系统评价和荟萃分析。
Lancet Infect Dis. 2020 Oct;20(10):1182-1192. doi: 10.1016/S1473-3099(20)30084-0. Epub 2020 May 26.
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Incidence of surgical site infection in dogs undergoing soft tissue surgery: risk factors and economic impact.接受软组织手术的犬类手术部位感染的发生率:危险因素及经济影响。
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Bilateral enucleation in dogs: A review of owner perceptions and satisfaction.犬类双侧眼球摘除术:主人认知与满意度综述
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6
A retrospective analysis of the risk factors for surgical site infections and long-term follow-up after transpalpebral enucleation in horses.马经睑摘除术后手术部位感染风险因素及长期随访的回顾性分析。
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Prospective surgical site infection surveillance in dogs.犬前瞻性手术部位感染监测
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犬眼球摘除术后手术部位感染的发生率及危险因素

Incidence and risk factors for surgical site infection following enucleation in dogs.

作者信息

Dacanay Samantha J, Barber Renee M, Diehl Kathryn A, Myrna Kathern E

机构信息

Department of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, GA, United States.

出版信息

Front Vet Sci. 2023 Jan 12;9:1086956. doi: 10.3389/fvets.2022.1086956. eCollection 2022.

DOI:10.3389/fvets.2022.1086956
PMID:36713880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9878593/
Abstract

INTRODUCTION

Surgical site infections (SSI) increase morbidity, increase treatment costs, and can delay onset of necessary adjunctive therapy. The goal of this retrospective study was to determine the incidence of and risk factors of SSI after enucleation in dogs.

METHODS

Medical records were searched at one veterinary teaching hospital and identified 280 dogs that underwent enucleation and had an adequate follow-up to assess SSI. Multiple preoperative (e.g., reason for enucleation), peri-operative (e.g., surgical approach and surgeon experience level), and post-operative (e.g., use of post-operative antibiotics or anti-inflammatory medications) variables were assessed as risk factors for development of SSI.

RESULTS

The incidence of SSI after enucleation was 5%, and no risk factors for SSI were identified. Dogs that received cephalexin as a prophylactic post-operative antibiotic were statistically more likely to develop SSI versus those that received a different post-operative antibiotic ( = 0.045). However, the clinical significance of this finding is unclear as administration of prophylactic post-operative antibiotics overall did not reduce the risk of SSI in the population evaluated here.

DISCUSSION

No risk factors were identified to guide clinical decision-making for prevention of SSI. Additionally, the results do not support the use of prophylactic antibiotics after enucleation in dogs.

摘要

引言

手术部位感染(SSI)会增加发病率、提高治疗成本,并可能延迟必要辅助治疗的开始时间。这项回顾性研究的目的是确定犬眼球摘除术后SSI的发生率及危险因素。

方法

在一家兽医教学医院检索病历,确定280只接受了眼球摘除术且有足够随访时间以评估SSI的犬。对多个术前(如眼球摘除的原因)、围手术期(如手术入路和外科医生经验水平)及术后(如术后抗生素或抗炎药物的使用)变量作为SSI发生的危险因素进行评估。

结果

眼球摘除术后SSI的发生率为5%,未发现SSI的危险因素。与接受其他术后抗生素的犬相比,接受头孢氨苄作为术后预防性抗生素的犬发生SSI的统计学可能性更高(P = 0.045)。然而,这一发现的临床意义尚不清楚,因为总体而言,术后预防性使用抗生素并未降低本研究评估人群中SSI的风险。

讨论

未发现指导预防SSI临床决策的危险因素。此外,研究结果不支持犬眼球摘除术后使用预防性抗生素。