Joseph Ruby, Venkatnarayan Kavitha, Nanaiah Ashitha, Ramachandran Priya
Department of Pulmonary Medicine, St. John's National Academy of Health Sciences, Bengaluru.
Department of Pathology, St. John's National Academy of Health Sciences, Bengaluru.
Monaldi Arch Chest Dis. 2023 Jan 27;93(4). doi: 10.4081/monaldi.2023.2472.
Mucormycosis is a fatal angio-invasive fungal infection associated with a high mortality. Apart from the traditional risk factors, COVID-19 infection and steroid therapy for the same have been recently identified to predispose to this life-threatening infection. Usual presentations of mucormycosis include rhino-orbito-cerebral, pulmonary, gastrointestinal, renal and cutaneous involvement. We report an unusual case of mediastinal involvement by mucormycosis in a patient recovering from moderate COVID-19 pneumonia. Early diagnosis, prompt initiation of antifungal therapy accompanied by timely surgical debridement were pivotal in averting morbidity and mortality in this patient.
毛霉病是一种致命的血管侵袭性真菌感染,死亡率很高。除了传统的风险因素外,最近发现新型冠状病毒肺炎(COVID-19)感染及其类固醇治疗易引发这种危及生命的感染。毛霉病的常见表现包括鼻眶脑型、肺型、胃肠型、肾型和皮肤型。我们报告了1例新型冠状病毒肺炎中度肺炎康复期患者发生纵隔毛霉病的罕见病例。早期诊断、及时启动抗真菌治疗并及时进行手术清创对于避免该患者发病和死亡至关重要。