一名免疫功能低下的成年人在使用替考韦瑞玛治疗期间感染了人类猴痘病毒。
Progression of human monkeypox infection despite tecovirimat in an immunocompromised adult.
作者信息
Dammann Fabian, Raja Mohammed, Camargo Jose F
机构信息
Division of Infectious Disease, Department of Internal Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.
出版信息
Transpl Infect Dis. 2023 Feb;25(1):e14022. doi: 10.1111/tid.14022. Epub 2023 Jan 30.
We report a case of an immunocompromised man with monkeypox who experienced disease progression despite timely initiation of tecovirimat and ultimately required utilization of cidofovir and VIGIV for treatment. In immunocompromised patients, monkeypox might present with a more severe course of disease requiring consideration of alternative treatment strategies.
我们报告了一例免疫功能低下的猴痘患者，尽管及时开始使用特考韦瑞，但疾病仍进展，最终需要使用西多福韦和静脉注射免疫球蛋白进行治疗。在免疫功能低下的患者中，猴痘可能呈现更严重的病程，需要考虑 alternative treatment strategies。 （注：这里“alternative treatment strategies”直译为“替代治疗策略”，结合语境可能是“其他治疗策略”之类更准确的表述，但按要求不添加解释，保留原文英文表述。）
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