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海湾合作委员会(GCC)慢性肾脏病和心力衰竭患者高钾血症的患病率和管理。

Prevalence and management of hyperkalemia in chronic kidney disease and heart failure patients in the Gulf Cooperation Council (GCC).

机构信息

Jahra Hospital, Jahra, Kuwait.

National Guard Hospital, Riyadh, Saudi Arabia.

出版信息

J Clin Hypertens (Greenwich). 2023 Mar;25(3):251-258. doi: 10.1111/jch.14633. Epub 2023 Jan 30.

Abstract

Hyperkalemia is a frequent complication in patients with chronic kidney disease (CKD) or heart failure (HF) and associated with neuromuscular manifestations, changes in the electrocardiogram, and increased risk of mortality. While data on the prevalence and management of hyperkalemia in the gulf region are scarce, risk factors such as preference for potassium-rich foods (e.g., dates and dried fruits/vegetables), periods of intense fasting (e.g., Ramadan), and diabetes (an ancestor of CKD and HF) are common. Therefore, a panel of nephrologists and cardiologists from countries of the Gulf Cooperation Council (GCC) convened to collate and review available data on the prevalence, regional drivers, and current practice in the management of hyperkalemia in the region. Eventually, this review provides consensus recommendations on a balanced utilization of dietary and pharmacological options including new potassium binders for achieving and sustainably maintaining desirable serum potassium levels in countries of the GCC region. Alignment with regional habits and practice was a key aspect to facilitate the uptake of the recommendations into physicians' practice and patients' lives.

摘要

高钾血症是慢性肾脏病(CKD)或心力衰竭(HF)患者的常见并发症,与神经肌肉表现、心电图变化和死亡率增加有关。虽然关于海湾地区高钾血症的患病率和管理的数据很少,但风险因素如喜欢富含钾的食物(如枣和干果/蔬菜)、长时间禁食(如斋月)和糖尿病(CKD 和 HF 的病因)很常见。因此,来自海湾合作委员会(GCC)国家的一组肾脏病专家和心脏病专家开会,整理和审查了该地区高钾血症的患病率、区域驱动因素和当前管理实践方面的现有数据。最终,该综述就平衡利用饮食和药物治疗方案(包括新型钾结合剂)提供了共识建议,以在 GCC 地区国家实现并可持续维持理想的血清钾水平。与区域习惯和实践保持一致是将这些建议纳入医生实践和患者生活的关键方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4afa/9994174/b91859eead1c/JCH-25-251-g001.jpg

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