Adebayo O, Ogah O S, Adebiyi A, Aje A, Adeoye A M, Oladapo O
Department of Medicine, Faculty of Clinical Sciences, University of Ibadan, Ibadan, Oyo State, Nigeria.
Cardiology Unit, Department of Medicine, Faculty of Clinical Sciences, University College Hospital, Ibadan, Oyo State, Nigeria.
West Afr J Med. 2023 Jan 30;40(1):30-44.
The burden of acute heart failure (AHF) is on the increase globally however, there are few studies on AHF in Nigeria and among black populations.
This study described the clinical profile, conventional management and six-months outcome after discharge of patients admitted for acute heart failure at the University College Hospital, Ibadan, Nigeria.
The study was a prospective study of 160 consecutive AHF patients. Socio-demographic details, clinical history, basic laboratory parameters electrocardiographic and echocardiographic parameters were assessed. They were followed-up for six-months after discharge to ascertain death or readmission.
The mean ± standard deviation (SD) age of all the patients was 58.0 ±15.1 years. Those aged 60 years and above constituted about half of the participants. Males comprised 59.3% and hypertension was the most common risk factor (77.5%). One hundred and thirty-four subjects (83.8%) were in New York Heart Association functional classes III or IV. The most common AHF type was heart failure with reduced ejection fraction and mostly presented de novo. The mean duration of admission was 11 days while intrahospital mortality and mortality at 6 months after discharge were 6.3% and 25.6% respectively.
This study provided a real-world data of AHF at UCH, Ibadan, Nigeria. It showed AHF was predominantly associated with hypertension. There was high mortality among these AHF subjects. There is a need for more strategy in our environment for preventing AHF and its adverse outcomes.
全球急性心力衰竭（AHF）的负担正在增加，然而，在尼日利亚和黑人人群中关于AHF的研究很少。
本研究描述了尼日利亚伊巴丹大学学院医院收治的急性心力衰竭患者出院后的临床特征、常规治疗及六个月结局。
本研究是一项对160例连续的AHF患者进行的前瞻性研究。评估了社会人口学细节、临床病史、基本实验室参数、心电图和超声心动图参数。出院后对他们进行了六个月的随访，以确定死亡或再次入院情况。
所有患者的平均年龄±标准差（SD）为58.0±15.1岁。60岁及以上的患者约占参与者的一半。男性占59.3%，高血压是最常见的危险因素（77.5%）。134名受试者（83.8%）属于纽约心脏协会功能分级III或IV级。最常见的AHF类型是射血分数降低的心力衰竭，且大多为新发。平均住院时间为11天，院内死亡率和出院后6个月的死亡率分别为6.3%和25.6%。
本研究提供了尼日利亚伊巴丹大学学院医院AHF的真实世界数据。研究表明AHF主要与高血压相关。这些AHF患者的死亡率很高。在我们的环境中需要更多预防AHF及其不良结局的策略。
