From the Department of Nuclear Medicine and PET-Centre, Aarhus University Hospital.
Clin Nucl Med. 2023 Apr 1;48(4):e198-e199. doi: 10.1097/RLU.0000000000004559. Epub 2023 Jan 31.
11 C-methionine PET/CT for parathyroid adenoma localization on a 60-year-old woman known with polycythemia vera revealed highly methionine-avid red bone marrow, an uptake pattern that has previously been described in hematological disease such as multiple myeloma. An equivalent skeletal "superscan" pattern in polycythemia vera has been described with other PET tracers, but this case illustrates that this pattern can be seen with 11 C-methionine PET/CT as well and can be added to the list of potential pitfalls.
11 C-蛋氨酸 PET/CT 用于定位一位 60 岁患有真性红细胞增多症的女性甲状旁腺腺瘤,结果显示骨髓对蛋氨酸摄取明显增高,这种摄取模式以前曾在多发性骨髓瘤等血液系统疾病中描述过。其他 PET 示踪剂也描述过真性红细胞增多症的这种“超级骨骼”摄取模式,但本病例说明,这种模式也可以用 11 C-蛋氨酸 PET/CT 显示出来,可以将其添加到潜在陷阱列表中。