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生长兔髌骨不稳定及早期复位后的髌骨发育

Patellar development after patella instability and early reduction in growing rabbits.

作者信息

Li Weifeng, Wang Qian, Wang Haiying, Zhang Zipeng, Wang Shunyi

机构信息

Department of Orthopaedic Surgery, Baoding No 1 Central Hospital, No. 320 Changcheng Street, Baoding, 071000, Hebei, People's Republic of China.

The First Department of Operating Room, Baoding No 1 Central Hospital, No. 320 Changcheng Street, Baoding, 071000, Hebei, People's Republic of China.

出版信息

BMC Musculoskelet Disord. 2023 Jan 30;24(1):78. doi: 10.1186/s12891-023-06183-6.

DOI:10.1186/s12891-023-06183-6
PMID:36717908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9885565/
Abstract

BACKGROUND

Patella-shaped disorder has been considered as a predisposing factor for patella instability. But the influence of early patella reduction for patellar development remains unclear. This study aimed to evaluate whether early operation in patella instability could improve patella morphology in growing rabbits.

METHODS

Fifty rabbits (1-month-old) were included in the study. The control group underwent no surgical procedures. The two experimental groups (reduction group and non-reduced group), underwent medial soft tissue restraint release surgery. The reduction group, rabbits underwent the medial soft tissue sutura surgery in order to stabilize the patella 2 months after release surgery. The non-reduced group, rabbits did not undergo suture surgery. Computed Tomography (CT) scans analysis in two experimental endpoints (2, 5 months after release surgery) were selected to evaluate the transverse diameter, thickness, Wiberg index and Wiberg angle. Gross observation was conducted to assess morphological changes of the patella.

RESULTS

CT scans showed significant difference in the mean transverse diameter, Wiberg angle between the two experimental groups and the control group 2 months after release surgery. 5 months after release surgery, the indices of patella were found no statistically difference in the reduction group versus the control group. However, the transverse diameter, Wiberg angle in the non-reduced group were significantly differences than that in the reduction group (P < 0.05). Gross observation showed a flattened articular surface of the patella in the non-reduced group.

CONCLUSIONS

The results indicated that patella instability may lead to patella-shaped disorder, showing a flattened morphology. Early patella reduction can improve the patella morphology in growing rabbits.

摘要

背景

髌骨形态紊乱被认为是髌骨不稳定的一个诱发因素。但早期髌骨复位对髌骨发育的影响仍不清楚。本研究旨在评估髌骨不稳定的早期手术是否能改善生长中兔的髌骨形态。

方法

本研究纳入50只1月龄兔。对照组未接受任何手术。两个实验组(复位组和未复位组)接受内侧软组织约束松解手术。复位组,兔在松解手术后2个月接受内侧软组织缝合手术以稳定髌骨。未复位组,兔未接受缝合手术。选择两个实验终点(松解手术后2、5个月)的计算机断层扫描(CT)分析来评估横径、厚度、Wiberg指数和Wiberg角。进行大体观察以评估髌骨的形态变化。

结果

CT扫描显示,松解手术后2个月,两个实验组与对照组之间的平均横径、Wiberg角存在显著差异。松解手术后5个月,复位组与对照组的髌骨指标无统计学差异。然而,未复位组的横径、Wiberg角与复位组相比有显著差异(P<0.05)。大体观察显示未复位组髌骨的关节面扁平。

结论

结果表明,髌骨不稳定可能导致髌骨形态紊乱,表现为扁平形态。早期髌骨复位可改善生长中兔的髌骨形态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/e185e781082e/12891_2023_6183_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/ef1656d597cf/12891_2023_6183_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/9048f9cfef72/12891_2023_6183_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/97e9153eda21/12891_2023_6183_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/e185e781082e/12891_2023_6183_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/ef1656d597cf/12891_2023_6183_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/9048f9cfef72/12891_2023_6183_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/97e9153eda21/12891_2023_6183_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8699/9885565/e185e781082e/12891_2023_6183_Fig4_HTML.jpg

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