Institute of Clinical Laboratory Diagnostics, University Hospital Centre Osijek, Osijek, Croatia.
Department of Chemistry, Biochemistry and Clinical Chemistry, Josip Juraj Strossmayer University of Osijek Faculty of Medicine, Osijek, Croatia.
Infect Dis (Lond). 2023 Apr;55(4):299-302. doi: 10.1080/23744235.2023.2172451. Epub 2023 Jan 30.
A rare case of coinfection of and SARS-CoV-2 disease in Croatia is presented in this report.
We tracked epidemiological and laboratory findings in a patient with SARS-CoV-2 and coinfection. A complete blood count was performed using the Sysmex XN-2000 analyser (Sysmex Corporation, Kobe, Japan), coagulation analyses were performed using the BCS XP coagulometer (Siemens Healthineers AG, Erlangen, Germany). Procalcitonin (PCT) and Interleukin-6 (IL-6) were measured by electrochemiluminescence immunoassay (ECLIA) using the Cobas e411 (Roche Diagnostics GmbH, Mannheim, Germany) analyser and high sensitivity troponin I (hsTnI) was measured using the Dimension EXL with LM analyser (Siemens Healthcare Diagnostics, Newark, USA). All other biochemistry analyses were performed using the Olympus AU680 (Beckman Coulter, Brea, California, USA) analyser. White blood cell differential analysis has been performed by examining the blood smear using the CellaVision DM1200 (CellaVision AB, Lund, Sweden) automatic analyser.
Even though the patient's initial health condition was disturbed, as a result of the physician's comprehensive anamnesis accompanied by laboratory findings, prompt diagnosis and appropriate therapy were assured, and consequently, the patient recovered.
In a pandemic, testing each febrile patient for the SARS-CoV-2 virus is of essential importance. However, the possibility of coinfection with another infectious disease agent cannot be disregarded.
本文报告了克罗地亚一例罕见的 和 SARS-CoV-2 疾病合并感染病例。
我们跟踪了一名 SARS-CoV-2 和 合并感染患者的流行病学和实验室发现。使用 Sysmex XN-2000 分析仪（Sysmex 公司，神户，日本）进行全血细胞计数，使用 BCS XP 凝血计（西门子健康公司，埃朗根，德国）进行凝血分析。使用 Cobas e411（罗氏诊断公司，曼海姆，德国）分析仪通过电化学发光免疫测定（ECLIA）测量降钙素原（PCT）和白细胞介素-6（IL-6），使用 Dimension EXL 与 LM 分析仪（西门子医疗诊断公司，纽瓦克，美国）测量高敏肌钙蛋白 I（hsTnI）。所有其他生化分析均使用 Olympus AU680（贝克曼库尔特，加利福尼亚州布雷亚）分析仪进行。使用 CellaVision DM1200（CellaVision AB，隆德，瑞典）自动分析仪通过检查血涂片进行白细胞分类分析。
尽管患者的初始健康状况受到干扰，但由于医生全面的病史检查和实验室发现，及时诊断和适当的治疗得到了保证，因此患者康复了。
在大流行期间，对每个发热患者进行 SARS-CoV-2 病毒检测至关重要。然而，不能忽视与另一种传染病原体合并感染的可能性。
