Department of Dermatology, First People's Hospital of Changshu City, Changshu Hospital Affiliated to Soochow University, Changshu, P. R. China.
Department of Dermatology, Affiliated Hospital of Nantong University, Nantong, P. R. China.
Am J Mens Health. 2023 Jan-Feb;17(1):15579883231152111. doi: 10.1177/15579883231152111.
The study aimed to understand the incidence, site, skin lesion manifestations, and treatment of gonococcal infection of the glans skin. We enrolled men with gonococcal infection of the glans skin and men with gonococcal urethritis from January 2014 to February 2020. Demographic data, site of onset, and skin lesion manifestations were recorded for all patients. Ceftriaxone (1 g) was injected intramuscularly once daily for 5 days in patients with lesions comprising abscesses or nodules. A single dose of ceftriaxone (1 g) was injected intramuscularly in patients with pustules. Incision and drainage were performed in patients with nonruptured abscesses. Thirteen patients had gonococcal infection of the glans skin (0.65%; 95% confidence interval = [0.30, 1.01]) among 1,989 patients with gonococcal urethritis. Mean age was 35.48 ± 2.37 (range = 26-45) years. Nonmarital sexual behavior patterns were genital-genital in eight patients (61.54%) and genital-oral in five patients (38.46%). All skin lesions occurred on the ventral side of the glans. Eleven patients (84.62%) had a single lesion and two (15.38%) had multiple lesions. The lesions manifested as abscesses in five patients (38.46%), nodules in five patients (38.46%), and pustules in three patients (23.08%). All lesions exhibited tenderness. All 13 patients were cured after treatment. The study shows that gonococcal infection of the glans skin is a rare local complication of gonorrhea. Lesions often occur on the ventral side of the glans, presenting as abscesses, nodules, and pustules. Ceftriaxone treatment was effective for gonococcal infection of the glans skin.
本研究旨在了解龟头皮肤淋病奈瑟菌感染的发病率、部位、皮肤损害表现和治疗方法。我们招募了 2014 年 1 月至 2020 年 2 月间患有龟头皮肤淋病奈瑟菌感染和淋病奈瑟菌尿道炎的男性患者。所有患者均记录人口统计学数据、发病部位和皮肤损害表现。对于包含脓肿或结节的病变患者，给予头孢曲松（1 g）每日 1 次肌内注射 5 天；对于脓疱患者，给予单次肌内注射头孢曲松（1 g）；对于未破裂的脓肿患者，进行切开引流。在 1989 例淋病奈瑟菌尿道炎患者中，有 13 例（0.65%；95%置信区间[0.30，1.01]）患有龟头皮肤淋病奈瑟菌感染。平均年龄为 35.48±2.37（范围=26-45）岁。8 例患者（61.54%）的非婚姻性行为模式为生殖器-生殖器，5 例患者（38.46%）为生殖器-口腔。所有皮肤损害均发生在龟头腹侧。11 例（84.62%）患者有单个皮损，2 例（15.38%）患者有多个皮损。皮损表现为 5 例（38.46%）脓肿、5 例（38.46%）结节和 3 例（23.08%）脓疱。所有皮损均有触痛。所有 13 例患者经治疗后均痊愈。本研究表明，龟头皮肤淋病奈瑟菌感染是淋病的一种罕见局部并发症。病变常发生在龟头腹侧，表现为脓肿、结节和脓疱。头孢曲松治疗对龟头皮肤淋病奈瑟菌感染有效。
