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拥抱模型系统的多样性,以剖析再生和组织修复的基础。

Embracing the diversity of model systems to deconstruct the basis of regeneration and tissue repair.

机构信息

Université Côte d'Azur, CNRS, INSERM, Institute for Research on Cancer and Aging (IRCAN), 06107 Nice, France.

Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

出版信息

Development. 2023 Feb 15;150(3). doi: 10.1242/dev.201579. Epub 2023 Jan 31.

DOI:10.1242/dev.201579
PMID:36718794
Abstract

The eighth EMBO conference in the series 'The Molecular and Cellular Basis of Regeneration and Tissue Repair' took place in Barcelona (Spain) in September 2022. A total of 173 researchers from across the globe shared their latest advances in deciphering the molecular and cellular basis of wound healing, tissue repair and regeneration, as well as their implications for future clinical applications. The conference showcased an ever-expanding diversity of model organisms used to identify mechanisms that promote regeneration. Over 25 species were discussed, ranging from invertebrates to humans. Here, we provide an overview of the exciting topics presented at the conference, highlighting novel discoveries in regeneration and perspectives for regenerative medicine.

摘要

第八届 EMBO 系列会议“再生和组织修复的分子和细胞基础”于 2022 年 9 月在西班牙巴塞罗那举行。来自全球的 173 名研究人员分享了他们在解码伤口愈合、组织修复和再生的分子和细胞基础方面的最新进展,以及这些进展对未来临床应用的影响。该会议展示了用于识别促进再生机制的不断扩展的模型生物多样性。讨论了超过 25 个物种,从无脊椎动物到人类。在这里,我们概述了会议上提出的令人兴奋的主题,强调了再生领域的新发现和再生医学的前景。

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Embracing the diversity of model systems to deconstruct the basis of regeneration and tissue repair.拥抱模型系统的多样性,以剖析再生和组织修复的基础。
Development. 2023 Feb 15;150(3). doi: 10.1242/dev.201579. Epub 2023 Jan 31.
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Repair, regenerate and reconstruct: meeting the state-of-the-art.修复、再生和重建:达到最新水平。
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Triggering the regeneration and tissue repair programs.触发再生和组织修复程序。
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Repair or regenerate--how can we tip the balance?修复还是再生——我们如何改变这种平衡?
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[New challenge of tissue repair and regenerative medicine: to achieve a perfect repair and regeneration of multiple tissues in wound sites].[组织修复与再生医学的新挑战:实现伤口部位多种组织的完美修复与再生]
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