Kastein Kim, Coe Kristi
Duke University School of Nursing, Durham, North Carolina (Ms Kastein and Dr Coe); and Moses Cone Health System, Neonatal Intensive Care Unit, Greensboro, North Carolina (Dr Coe).
Adv Neonatal Care. 2023 Apr 1;23(2):160-166. doi: 10.1097/ANC.0000000000001040. Epub 2023 Jan 31.
Air leaks, especially pulmonary interstitial emphysema (PIE), are increasingly uncommon respiratory complications of the newborn. Despite PIE having a decreasing incidence, it continues to have a high morbidity and mortality rate. This makes PIE one of the most severe respiratory complications to affect a newborn. Air leaks occur when there is overdistension of the terminal airways or alveoli, which results in air dissecting into extra-alveolar spaces. Recognizing the signs of air leaks is paramount to allow for appropriate diagnosis and treatment of the newborn to improve morbidity and mortality. Treatment modalities range from positioning the newborn in the decubitus position to surgical intervention.
To summarize current evidence on the pathophysiology, risk factors, diagnosis, treatment, and management of PIE and pneumothorax.
Two databases were systematically reviewed with key words later. Articles in English with date restrictions from 2016 to current were included.
Inclusion criteria of randomized controlled trials, case studies/reports, and review articles were utilized. Twenty articles, primarily case reports and studies, were reviewed.
Guidelines for data abstraction were followed via independent extraction by a single observer.
Qualitative results were utilized to formulate current treatment of air leaks.
This article provides guidance for frontline neonatal providers on current treatment and management of air leaks in the newborn population.
气漏,尤其是肺间质气肿(PIE),是新生儿中越来越少见的呼吸道并发症。尽管PIE的发病率在下降,但它仍然具有较高的发病率和死亡率。这使得PIE成为影响新生儿的最严重呼吸道并发症之一。当终末气道或肺泡过度扩张,导致空气进入肺泡外间隙时,就会发生气漏。识别气漏的迹象对于新生儿的正确诊断和治疗以改善发病率和死亡率至关重要。治疗方式从将新生儿置于卧位到手术干预不等。
总结关于PIE和气胸的病理生理学、危险因素、诊断、治疗和管理的当前证据。
稍后使用关键词对两个数据库进行系统综述。纳入2016年至今有日期限制的英文文章。
采用随机对照试验、病例研究/报告和综述文章的纳入标准。对20篇文章进行了综述,主要是病例报告和研究。
由一名观察者独立提取数据,遵循数据摘要指南。
采用定性结果来制定当前气漏的治疗方法。
本文为一线新生儿医疗人员提供了关于新生儿气漏当前治疗和管理的指导。