在无菌大鼠中，甘氨酸酰胺化胆汁盐不会发生去结合作用。
Deconjugation of glycine-amidated bile salts does not occur in germfree rats.
作者信息
Borgström B, Midtvedt T, Corrie M
机构信息
Department of Physiological Chemistry, University of Lund, Sweden.
出版信息
Scand J Clin Lab Invest. 1987 Oct;47(6):551-3. doi: 10.1080/00365518709168467.
PMID:3672028
Abstract
After oral administration to germfree rats of cholyl-glycine-1-14C, deoxycholyl-glycine-1-14C and nor-ursocholyl-glycine-1-14C no significant amounts of 14CO2 are expired. This indicates that these bile salts are not significantly deamidated under physiological conditions in the rat organism outside the gastro-intestinal tract.
摘要
向无菌大鼠口服胆酰甘氨酸 -1-¹⁴C、脱氧胆酰甘氨酸 -1-¹⁴C 和去甲熊胆酰甘氨酸 -1-¹⁴C 后，呼出的¹⁴CO₂量并不显著。这表明在大鼠机体胃肠道外的生理条件下，这些胆汁盐不会发生显著的脱酰胺反应。
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