炎症性癫痫（FIRES）与噬血细胞性淋巴组织细胞增生症（HLH）：一例成人病例
Inflammatory epilepsy (FIRES) and haemophagocytic lymphohistiocytosis (HLH): an adult case.
作者信息
Kam Ian, Prentice David, Kho Lay Kun, Dharsono Ferry
机构信息
Neurology, Royal Perth Hospital, Perth, Western Australia, Australia
Neurology, Perron Institute for Neurological and Translational Science, Nedlands, Western Australia, Australia.
出版信息
BMJ Case Rep. 2023 Jan 31;16(1):e252637. doi: 10.1136/bcr-2022-252637.
Abstract
We describe a man in his 30s with haemophagocytic lymphohistiocytosis (HLH), secondary to an upper respiratory tract infection, with subsequent febrile infection-related epilepsy syndrome. He had a prolonged hospital admission, during which he was treated with chemotherapy for HLH and antiepileptic medications for refractory seizures. He was discharged fully dependent to a care facility and died from aspiration pneumonia 11 months later. This case report highlights his management and discusses these conditions' pathophysiology and future management.
摘要
我们描述了一名30多岁的男性，患有噬血细胞性淋巴组织细胞增生症（HLH），继发于上呼吸道感染，随后出现发热性感染相关癫痫综合征。他住院时间延长，在此期间接受了针对HLH的化疗和针对难治性癫痫发作的抗癫痫药物治疗。出院时他完全依赖护理机构，11个月后死于吸入性肺炎。本病例报告重点介绍了他的治疗情况，并讨论了这些病症的病理生理学及未来治疗方法。
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