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[左外叶及左尾状叶包裹胃十二指肠动脉残端预防腹腔镜胰十二指肠切除术后出血的初步研究]

[A preliminary study on the prevention of hemorrhage after laparoscopic pancreaticoduodenectomy by wrapping gastroduodenal artery stump in the left external liver lobe and the left caudate lobe].

作者信息

Zhang S B, Zhou X B, Hu Z X, Xing Z Z, Liu J H

机构信息

Department of Hepatobiliary Surgery,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China.

出版信息

Zhonghua Wai Ke Za Zhi. 2023 Feb 1;61(2):145-149. doi: 10.3760/cma.j.cn112139-20220623-00280.

Abstract

To investigate the safety and efficacy of embedding the stump of gastroduodenal artery between the left lateral lobe of the liver and the left caudate lobe to prevent bleeding after laparoscopic pancreaticoduodenectomy. The clinical data of 41 patients who underwent laparoscopic pancreaticoduodenectomy at the second Hospital of Hebei Medical University from October 2021 to April 2022 were analyzed retrospectively.There were 27 males and 14 females, aged (63.0±9.2)years (range: 48 to 78 years), and the body mass index was (24.1±3.2)kg/m (range: 15.4 to 31.6 kg/m). After routine laparoscopic pancreaticoduodenectomy, the stump of gastroduodenal artery was embedded between the left lateral lobe and the left caudate lobe of the liver, and the hepatic parenchyma of the left lateral lobe and the left caudate lobe were sutured with absorbable sutures.The occurrence and recovery of postoperative complications (pancreatic fistula, biliary fistula, postoperative abdominal bleeding, abdominal infection, liver abscess) were observed. All the operations of 41 patients were completed successfully.The operation time was (277.5±52.0) minutes (range: 192 to 360 minutes). The entrapment time of gastroduodenal artery stump was (3.1±0.6) minutes (range: 2.3 to 4.2 minutes), and the intraoperative blood loss ((IQR)) was 300 (200) ml (range: 50 to 800 ml).The results of ultrasound examination of hepatic artery on the first day after operation showed that the blood flows of hepatic artery were unobstructed.Postoperative pancreatic fistula occurred in 3 cases, including grade B pancreatic fistula in 2 cases (1 case with abdominal infection) and biochemical leakage in 1 case. Three patients with pancreatic fistula were discharged successfully after continuous abdominal drainage. There was no biliary fistula, abdominal bleeding, abdominal infection, liver abscess or postoperative liver dysfunction. The encasement of the gastroduodenal artery stump by the left outer and left caudate lobes of the liver may be an effective way to prevent bleeding from the rupture of the gastroduodenal artery stump after laparoscopic pancreatoduodenectomy, which is easy and safe to perform.

摘要

探讨将胃十二指肠动脉残端埋入肝左外叶与左尾状叶之间预防腹腔镜胰十二指肠切除术后出血的安全性及有效性。回顾性分析2021年10月至2022年4月在河北医科大学第二医院行腹腔镜胰十二指肠切除术的41例患者的临床资料。其中男性27例,女性14例,年龄(63.0±9.2)岁(范围:48至78岁),体重指数为(24.1±3.2)kg/m²(范围:15.4至31.6 kg/m²)。常规腹腔镜胰十二指肠切除术后,将胃十二指肠动脉残端埋入肝左外叶与左尾状叶之间,用可吸收缝线缝合肝左外叶和左尾状叶的肝实质。观察术后并发症(胰瘘、胆瘘、术后腹腔出血、腹腔感染、肝脓肿)的发生及恢复情况。41例患者手术均顺利完成。手术时间为(277.5±52.0)分钟(范围:192至360分钟)。胃十二指肠动脉残端包埋时间为(3.1±0.6)分钟(范围:2.3至4.2分钟),术中出血量(四分位数间距)为300(200)ml(范围:50至800 ml)。术后第1天肝动脉超声检查结果显示肝动脉血流通畅。术后发生胰瘘3例,其中B级胰瘘2例(1例合并腹腔感染),生化漏1例。3例胰瘘患者经持续腹腔引流后均顺利出院。无胆瘘、腹腔出血、腹腔感染、肝脓肿及术后肝功能障碍发生。肝左外叶和左尾状叶对胃十二指肠动脉残端的包埋可能是预防腹腔镜胰十二指肠切除术后胃十二指肠动脉残端破裂出血的有效方法,操作简便、安全。

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