Shaare Zedek Medical Center, Jerusalem, Israel.
Department of Pediatrics, Hebrew University of Jerusalem Medical School, Jerusalem, Israel.
J Perinatol. 2023 Mar;43(3):300-304. doi: 10.1038/s41372-023-01624-5. Epub 2023 Jan 31.
Minimally Invasive Surfactant Treatment (MIST) is a common method for administering surfactant as a treatment for respiratory distress syndrome. However, tracheal catheter placement can be difficult to confirm. We assessed the presence of carbon dioxide (CO) in tracheal and esophageal gas aspirated using CO detector.
Retrospective arm: 20 infants, MIST catheter placement was assessed with a CO detector in two techniques and confirmed with clinical response. Prospective arm-10 infants, aimed to check for CO presence in aspirated esophageal gas during routine nasogastric tube insertion.
Retrospective arm: All infants had positive capnography. One infant that had no clinical response to MIST was diagnosed with total anomalous pulmonary venous return. All 10 infants of the prospective arm had a Negative capnography (P < 0.001, Fisher's exact test).
Readily available CO detectors can distinguish between tracheal and esophageal placement of MIST catheters prior to MIST.
微创表面活性剂治疗（MIST）是一种常见的表面活性剂给药方法，用于治疗呼吸窘迫综合征。然而，气管导管的位置确认可能具有一定难度。我们使用二氧化碳（CO）探测器来评估从气管和食管抽吸气体中 CO 的存在。
回顾性组：20 名婴儿，使用 CO 探测器评估两种技术中的 MIST 导管位置，并通过临床反应进行确认。前瞻性组 1-10 名婴儿，旨在检查常规鼻胃管插入过程中从食管抽吸气体中 CO 的存在。
回顾性组：所有婴儿的呼气末二氧化碳描记图均为阳性。1 名对 MIST 无临床反应的婴儿被诊断为完全性肺静脉异常回流。前瞻性组的 10 名婴儿的呼气末二氧化碳描记图均为阴性（P < 0.001，Fisher 确切检验）。
现成的 CO 探测器可在 MIST 之前区分 MIST 导管的气管和食管位置。
