Rothschild Foundation Hospital, department of Neuro-Ophthalmology, 29 rue Manin, 75940, Paris, Cedex 19, France.
Sorbonne Université, Faculté de Médecine, 91 Boulevard de l' l'Hôpital, 75013, Paris, France.
Eye (Lond). 2023 Sep;37(13):2776-2780. doi: 10.1038/s41433-023-02419-w. Epub 2023 Jan 31.
Assess the prevalence and evolution of PHOMS in optic neuritis.
We analysed the medical files of 126 patients included in the OCTON cohort. Patients' medical files, digital retinal images and OCT examinations were reviewed, searching for optic nerve head oedema and PHOMS at the initial presentation and during the follow-up.
We included 102 patients in the final analysis. Twenty-nine (29) eyes had optic nerve head oedema at the initial presentation. PHOMS were found to be present in 8 eyes affected with optic neuritis. All cases of PHOMS were associated with optic nerve head oedema. All the PHOMS decreased in size and disappeared with the improvement of the oedema.
Our results show that PHOMS is not a common sign of optic neuritis. We didn't observe any case of PHOMS in the absence of optic nerve head oedema in eyes with optic neuritis. PHOMS seem to be a rare sign of optic neuritis associated to optic nerve head oedema, and they tend to disappear with the improvement of the optic nerve head oedema. We suggest that the presence of PHOMS in optic neuritis eyes with no optic nerve oedema should be a considered warning sign.
评估 PHOMS 在视神经炎中的发生率和演变情况。
我们分析了 OCTON 队列中纳入的 126 名患者的病历。对患者的病历、数字视网膜图像和 OCT 检查进行了回顾，以寻找初次就诊时和随访期间视神经头水肿和 PHOMS 的存在。
我们最终分析了 102 名患者。29 只眼睛在初次就诊时出现视神经头水肿。在患有视神经炎的 8 只眼中发现存在 PHOMS。所有 PHOMS 均与视神经头水肿相关。所有 PHOMS 的大小均随着水肿的改善而减小并消失。
我们的结果表明，PHOMS 不是视神经炎的常见征象。我们在视神经炎眼中没有观察到任何没有视神经头水肿的 PHOMS 病例。PHOMS 似乎是视神经头水肿相关的视神经炎的罕见征象，随着视神经头水肿的改善，它们往往会消失。我们建议，在没有视神经头水肿的视神经炎眼中出现 PHOMS 应被视为一个警示信号。
