Kumar Sudesh, Sah Surendra, Ray Prajna, Bhattacharya Piyali, Chatterjee Nandita
Pediatrics, Mata Gujri Memorial Medical College, Kishanganj, IND.
Cureus. 2022 Dec 29;14(12):e33091. doi: 10.7759/cureus.33091. eCollection 2022 Dec.
Although infantile tremor syndrome is considered a rare entity, we present a typical case of this disorder. This case reinforces the association of infantile tremor syndrome with exclusive breastfeeding in infants and the absence of proper complementary feeding. A nine-month-old, irritable, listless, exclusively breastfed female presented with grade 2 malnutrition, tremors, hyperpigmentation, scarce scalp hair, and delayed developmental milestones. Laboratory investigations revealed macrocytic anemia and a low serum vitamin B12 value of 205 pg/dL. Cerebral and mild cerebellar atrophy were noted on the MRI brain scan. Accordingly, the patient was diagnosed with infantile tremor syndrome and treated with vitamin B12 and nutrient supplementation with zinc, magnesium, folic acid, and iron. The tremors improved and the child became responsive and interested in her surroundings. It is essential to recognize this condition at the earliest and initiate treatment. Basic interventions such as the promotion of proper nutrition, timely introduction of complementary feeding, and weaning practices are key factors in decreasing the incidence of this condition.
尽管婴儿震颤综合征被认为是一种罕见病症，但我们仍呈现了该疾病的一个典型病例。此病例强化了婴儿震颤综合征与婴儿纯母乳喂养以及缺乏适当辅食喂养之间的关联。一名九个月大、烦躁、无精打采、纯母乳喂养的女婴，出现了二级营养不良、震颤、色素沉着、头皮毛发稀少以及发育里程碑延迟的情况。实验室检查显示大细胞性贫血，血清维生素B12值低至205 pg/dL。脑部MRI扫描显示大脑和轻度小脑萎缩。据此，该患者被诊断为婴儿震颤综合征，并接受了维生素B12以及锌、镁、叶酸和铁的营养补充治疗。震颤症状有所改善，患儿变得反应灵敏并对周围环境产生了兴趣。尽早识别这种病症并开始治疗至关重要。诸如促进适当营养、及时引入辅食喂养以及断奶措施等基本干预措施是降低该病症发病率的关键因素。
