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低剂量甲氨蝶呤致结肠炎和全血细胞减少症患者的不寻常表现。

An Unusual Presentation of a Patient With Low-Dose Methotrexate Causing Colitis and Pancytopenia.

作者信息

R Ramya, Malic Nikola, Menon Trishala, Marks Edward, Machani Sathyanarayana

机构信息

Family Medicine, WVU Medicine Wheeling Hospital, Wheeling, USA.

Family Medicine, WVU Medicine Uniontown Hospital, Uniontown, USA.

出版信息

Cureus. 2022 Dec 28;14(12):e33062. doi: 10.7759/cureus.33062. eCollection 2022 Dec.

Abstract

This paper summarizes the case of a patient admitted to the hospital due to methotrexate-induced colitis in the setting of pancytopenia. Although methotrexate is commonly used for a variety of diseases, this medication can precipitate side effects in a subset of patients. This is an atypical case of chronic low-dose methotrexate use leading to colitis and pancytopenia. It is of utmost significance to monitor patients on methotrexate through routine laboratory checks such as complete blood counts and liver function tests to ensure safety and reduce mortality.

摘要

本文总结了一名因甲氨蝶呤诱发的结肠炎合并全血细胞减少症而入院的患者病例。尽管甲氨蝶呤常用于多种疾病,但这种药物会在一部分患者中引发副作用。这是一例因长期低剂量使用甲氨蝶呤导致结肠炎和全血细胞减少症的非典型病例。通过全血细胞计数和肝功能检查等常规实验室检查来监测使用甲氨蝶呤的患者,对于确保安全和降低死亡率至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b4e/9883061/373f06f0b969/cureus-0014-00000033062-i01.jpg

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