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一项基于社区的新型治疗教育项目,旨在减少酒精使用障碍患者与酒精相关的危害和污名化:一项准实验研究(ETHER研究)。

A novel community-based therapeutic education program for reducing alcohol-related harms and stigma in people with alcohol use disorders: A quasi-experimental study (ETHER study).

作者信息

Barré Tangui, Ramier Clémence, Antwerpes Saskia, Costa Marie, Bureau Morgane, Maradan Gwenaelle, Di Beo Vincent, Cutarella Christophe, Leloutre Jacques, Riccobono-Soulier Olivier, Hedoire Sophie, Frot Elodie, Vernier Fabienne, Vassas-Goyard Stéphanie, Dufort Sabine, Protopopescu Camelia, Marcellin Fabienne, Casanova Danielle, Coste Marion, Carrieri Patrizia

机构信息

Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, ISSPAM, Marseille, France.

Clinique Saint-Barnabé, Marseille, France.

出版信息

Drug Alcohol Rev. 2023 Mar;42(3):664-679. doi: 10.1111/dar.13605. Epub 2023 Jan 31.

Abstract

INTRODUCTION

Alcohol use disorder (AUD) is associated with a significant disease burden in France, where alcohol use is deeply rooted in culture. However, the treatment gap is large because of several barriers, including stigmatisation and drinkers' apprehension about total abstinence. However, standardised and evidence-based interventions based on controlled-drinking for people with AUD are lacking. We aimed to assess the effectiveness of a novel community-based French therapeutic patient education (TPE) program for people with AUD named Choizitaconso.

METHODS

A before-after non-randomised quasi-experimental study, named ETHER, was designed and implemented with people living with AUD, over a period of 6 months. The primary outcome was percentage change in the number of alcohol-related harms experienced. Secondary outcomes were percentage changes in psycho-social patient-reported and community-validated outcomes. Participants in the intervention group (n = 34) benefited from the 10-week TPE program Choizitaconso, while the comparison group (n = 58) received standard care. The Kruskall-Wallis and chi-squared or Fisher's exact tests were used to compare before-after changes in variables in both groups. Linear regression models were used to test for the effect of study group on each outcome and to test for the effect of alcohol consumption as a confounder.

RESULTS

At 6 months, all outcomes but one either remained stable or numerically improved in both groups. Internalised stigma significantly improved in the intervention group (p = 0.026) but not in the comparison group (p = 0.207), with a significant group effect (p = 0.014).

DISCUSSION AND CONCLUSIONS

This study demonstrates the effectiveness of the Choizitaconso TPE program on community-validated outcomes, especially internalised stigma.

摘要

引言

酒精使用障碍(AUD)在法国与重大疾病负担相关,在法国,饮酒深深植根于文化之中。然而,由于包括污名化和饮酒者对完全戒酒的担忧在内的多种障碍,治疗缺口很大。然而,针对酒精使用障碍患者基于控制饮酒的标准化且有循证依据的干预措施却很缺乏。我们旨在评估一项名为Choizitaconso的针对酒精使用障碍患者的新型社区法国治疗性患者教育(TPE)项目的有效性。

方法

一项名为ETHER的前后非随机准实验研究,针对酒精使用障碍患者开展,为期6个月。主要结局是经历的与酒精相关危害数量的百分比变化。次要结局是患者报告的心理社会结局和经社区验证的结局的百分比变化。干预组(n = 34)的参与者受益于为期10周的Choizitaconso TPE项目,而对照组(n = 58)接受标准护理。采用Kruskal-Wallis检验和卡方检验或Fisher精确检验来比较两组变量的前后变化。使用线性回归模型来检验研究组对每个结局的影响,并检验饮酒作为混杂因素的影响。

结果

在6个月时,除一项结局外,两组的所有结局要么保持稳定,要么在数值上有所改善。干预组的内化污名显著改善(p = 0.026),而对照组未改善(p = 0.207),存在显著的组间效应(p = 0.014)。

讨论与结论

本研究证明了Choizitaconso TPE项目在经社区验证的结局方面的有效性,尤其是在内化污名方面。

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