Cardiac Anaesthesia, Ozone Anaesthesia Group, Aurangabad, Maharashtra, India.
Department of Cardiothoracic Anaesthesiology, Army Institute of Cardiothoracic Sciences, Pune, Maharashtra, India.
Ann Card Anaesth. 2023 Jan-Mar;26(1):42-49. doi: 10.4103/aca.aca_20_21.
Left ventricular (LV) diastolic dysfunction is common on preoperative screening among patients undergoing surgery. There is no simple screening test at present to suspect LV diastolic dysfunction. This study was aimed to test the hypothesis, whether elastic recoil signal (ERS) on tissue Doppler imaging of mitral annulus (MA TDI) can be used as a qualitative test to differentiate patients from normal LV diastolic function versus patients with LV diastolic dysfunction.
This was a prospective cross-sectional observational study of patients admitted for elective surgeries. Normal diastolic function and categorization of LV diastolic dysfunction into severity grades I, II, or III were performed as per the American Society of Echocardiography/ European Associationof Cardio Vascular Imaging (ASE/EACVI) recommendations for LV diastolic dysfunction.
There were 41 (61%) patients with normal LV diastolic function and 26 (39%) patients with various grades of LV diastolic dysfunction. In 38 out of 41 patients with normal LV diastolic function, the characteristic ERS was identified. The ERS was absent in all the patients with any grade of LV diastolic dysfunction. Consistency of identification of ERS on echocardiography was tested with a good interobserver variability coefficient of 0.94 (P-value <0.001). The presence of ERS demonstrated an excellent differentiation to rule out any LV diastolic dysfunction with an area under the receiver operating characteristics curve (AUROC) of 0.96 (CI 0.88-0.99; P value <0.001).
To conclude, in a mixed surgical population, the anesthetist could successfully assess LV diastolic dysfunction in the preoperative period and the characteristic ERS on MA TDI signal can be used as a qualitative test to differentiate patients from normal LV diastolic function versus patients with LV diastolic dysfunction using the transthoracic echocardiography (TTE).
在接受手术的患者的术前筛查中,左心室(LV)舒张功能障碍很常见。目前尚无简单的筛查试验来怀疑 LV 舒张功能障碍。本研究旨在检验以下假设,即二尖瓣环(MA TDI)组织多普勒成像上的弹性回弹信号(ERS)是否可作为一种定性试验,用于区分具有正常 LV 舒张功能的患者与具有 LV 舒张功能障碍的患者。
这是一项对择期手术患者进行的前瞻性横断面观察性研究。根据美国超声心动图学会/欧洲心血管影像协会(ASE/EACVI)对 LV 舒张功能障碍的建议,对正常舒张功能和 LV 舒张功能障碍的严重程度分级 I、II 或 III 进行分类。
41 例(61%)患者具有正常 LV 舒张功能,26 例(39%)患者具有不同程度的 LV 舒张功能障碍。在 41 例具有正常 LV 舒张功能的患者中,有 38 例识别出特征性的 ERS。所有存在任何程度 LV 舒张功能障碍的患者均不存在 ERS。ERS 在心超检查中的识别一致性经检验具有良好的观察者间变异系数为 0.94(P<0.001)。ERS 的存在对排除任何 LV 舒张功能障碍具有出色的鉴别作用,其接受者操作特征曲线下面积(AUROC)为 0.96(CI 0.88-0.99;P<0.001)。
总之,在混合手术人群中,麻醉师可以成功评估术前的 LV 舒张功能障碍,MA TDI 信号上的特征性 ERS 可用作定性试验,以区分具有正常 LV 舒张功能的患者与具有 LV 舒张功能障碍的患者,该试验采用经胸超声心动图(TTE)进行。