[Effect of actinomycin D on the survival and recovery capacity of irradiated connective tissue cells in the Chinese hamster].
作者信息
Ziegler W
机构信息
Strahlenbiologisches Institut der Ludwig-Maximilians-Universität, München.
出版信息
Strahlenther Onkol. 1987 Oct;163(10):681-6.
PMID:3672316
Abstract
Simultaneous treatment of Chinese hamster fibroblasts with Actinomycin D and gamma rays under normal aerobic conditions leads to radiosensitization. In contrast to Actinomycin D pretreatment, modification to the effect of radiation is drug dose dependent in the case of post-treatment. No effect of Actinomycin D upon the shape of the radiation cell survival curve is seen under hypoxic conditions. Recovery from radiation damage in split dose experiments is not influenced by the drug.
摘要
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