Badalian G O, Episkoposian N G, Amatuni G V
Ter Arkh. 1987;59(7):92-5.
It was shown that fructose-1.6-diphosphate was capable of marked suppression of the aggregation power of the blood erythrocytes of patients with acute myocardial infarction and angina of effort. The antiaggregation effect of the drug was dose-related and enhanced with an increase in the time of its contact with erythrocytes. The antiaggregation effect of pentoxifylline was not of distinct dose-related nature. Its antiaggregation power did not considerably depend on the time of incubation with erythrocytes.
结果表明,1,6 - 二磷酸果糖能够显著抑制急性心肌梗死患者和劳力性心绞痛患者血液红细胞的聚集能力。该药物的抗聚集作用与剂量相关,并且随着其与红细胞接触时间的增加而增强。己酮可可碱的抗聚集作用不具有明显的剂量相关性。其抗聚集能力在很大程度上不依赖于与红细胞孵育的时间。