使用1分钟坐立试验检测间质性肺疾病患者的气体交换受损情况。
Detection of impaired gas exchange using the 1-minute sit-to-stand test in patients with interstitial lung disease.
作者信息
Oishi Keiji, Asami-Noyama Maki, Yamamoto Tasuku, Matsumori Kosuke, Yonezawa Kosei, Watanabe Michiya, Hisamoto Yukari, Fukatsu Ayumi, Matsuda Kazuki, Hamada Kazuki, Suetake Ryo, Ohata Syuichiro, Murata Yoriyuki, Yamaji Yoshikazu, Sakamoto Kenji, Ito Kosuke, Osoreda Hisayuki, Edakuni Nobutaka, Kakugawa Tomoyuki, Hirano Tsunahiko, Matsunaga Kazuto
机构信息
Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
Department of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube, Japan.
出版信息
Respir Investig. 2023 Mar;61(2):186-189. doi: 10.1016/j.resinv.2022.12.009. Epub 2023 Jan 30.
BACKGROUND
Although pulmonary function tests (PFTs) are important in patients with interstitial lung disease (ILD), they cannot be easily performed in a primary healthcare setting. This study aimed to examine the usefulness of the difference between pulse oxygen saturation (SpO2) at rest and the lowest SpO2 during the 1-min sit-to-stand test (delta SpO2-1STST) for predicting pulmonary function impairment.
METHODS
We retrospectively reviewed 116 patients with ILD who underwent 1STST and PFTs.
RESULTS
The delta SpO2-1STST and diffusing capacity for carbon monoxide (DLco) strongly correlated (ρ = 0.70). The delta SpO2-1STST was effective in predicting impaired gas exchange (cut-off value, -4%; AUC, 0.86; sensitivity, 74%; specificity, 87%).
CONCLUSIONS
The Delta SpO2-1STST may be a reasonable tool for predicting abnormalities in PFTs.
背景
尽管肺功能测试（PFTs）对间质性肺疾病（ILD）患者很重要，但在基层医疗环境中不易进行。本研究旨在探讨静息脉搏血氧饱和度（SpO2）与1分钟坐立试验期间最低SpO2之间的差值（SpO2-1STST差值）对预测肺功能损害的有用性。
方法
我们回顾性分析了116例行1STST和PFTs的ILD患者。
结果
SpO2-1STST差值与一氧化碳弥散量（DLco）密切相关（ρ = 0.70）。SpO2-1STST差值在预测气体交换受损方面有效（截断值为-4%；AUC为0.86；敏感性为74%；特异性为87%）。
结论
SpO2-1STST差值可能是预测PFTs异常的合理工具。
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