Tibboel D, Affourtit M J
Kinderchirurgische Intensive Care, Sophia Kinderziekenhuis, Rotterdam.
Tijdschr Kindergeneeskd. 1987 Aug;55(4):150-4.
The short bowel syndrome is a clinical picture, consisting of malabsorption and failure to thrive, in consequence of a resection of more than 50% of the small bowel, with or without resection of a part of the colon. The etiology, pathophysiology, treatment and natural history are discussed, as well as complications and ultimate prognosis. A review of the literature and own retrospective investigation prove, that after an extensive small bowel resection in the neonatal period, normal stools, growth and development can occur in 1-3 years. In the first, postoperative period however, these patients suffer from considerable malabsorption, deficiencies of vitamins and trace elements, as well as complications of total parenteral nutrition and recurrent infections.
短肠综合征是一种临床表现,因小肠切除超过50%(无论有无部分结肠切除)而导致吸收不良和生长发育迟缓。本文讨论了其病因、病理生理学、治疗方法、自然病程,以及并发症和最终预后。文献综述和自身回顾性研究证明,新生儿期广泛小肠切除术后,1至3年内可出现正常排便、生长和发育。然而,在术后初期,这些患者会出现严重的吸收不良、维生素和微量元素缺乏,以及全胃肠外营养并发症和反复感染。