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硬脊膜内髓外脑膜黑素细胞瘤:一例报告及文献复习

Intradural extramedullary meningeal melanocytoma: a case report and literature review.

作者信息

Parwez Rabeeia, Ahmed Razna, Baig Arsalan, Ruiz Fernanda, Baig Mirza Asfand, Sadek Ahmed-Ramadan, Arvin Babak, Qureshi Anjum

机构信息

Department of Neurosurgery, Queens Hospital Romford, London, UK.

GKT School of Medical Education, King's College London, London, UK.

出版信息

J Surg Case Rep. 2023 Jan 26;2023(1):rjad002. doi: 10.1093/jscr/rjad002. eCollection 2023 Jan.

DOI:10.1093/jscr/rjad002
PMID:36727122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9880139/
Abstract

Primary meningeal melanocytomas are extremely rare, benign tumours arising from the leptomeninges. While they are considered to be benign lesions, there is potential for their growth and transformation into malignant melanomas. They are commonly found in the cervical spine, with a decreased incidence in the thoracic and lumbar regions. We present a case report of a 56-year-old man who presented to our unit with a 4-month history of lower limb weakness and a sensory level at T6. Magnetic resonance imaging shows an intradural extramedullary tumour. The patient underwent a thoracic debulking of the lesion with neurophysiological monitoring. Histopathology confirmed the diagnosis of melanocytoma of meningeal origin, with a low mitotic count. Our patient recovered well post-operatively with no complications. Surgical resection is an effective method to manage this tumour; however, adjuvant radiotherapy is advised due to the risk of recurrence and malignant transformation.

摘要

原发性脑膜黑素细胞瘤极为罕见,是起源于柔脑膜的良性肿瘤。虽然它们被认为是良性病变,但仍有生长并转化为恶性黑色素瘤的可能。它们常见于颈椎,在胸椎和腰椎区域的发病率较低。我们报告一例56岁男性病例,该患者因下肢无力4个月及T6感觉平面异常前来我院就诊。磁共振成像显示硬膜内髓外肿瘤。患者在神经生理监测下接受了胸椎病变减瘤手术。组织病理学确诊为脑膜起源的黑素细胞瘤,有丝分裂计数较低。我们的患者术后恢复良好,无并发症。手术切除是治疗该肿瘤的有效方法;然而,由于存在复发和恶性转化的风险,建议进行辅助放疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/ff6bf5ce265d/rjad002f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/c06e55673589/rjad002f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/fac2883bac4a/rjad002f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/d4d49f32c1a6/rjad002f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/ff6bf5ce265d/rjad002f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/c06e55673589/rjad002f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/fac2883bac4a/rjad002f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/d4d49f32c1a6/rjad002f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e6e/9880139/ff6bf5ce265d/rjad002f4.jpg

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