Smt. Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Department of Eye Smart EMR & AEye, L V Prasad Eye Institute; Indian Health Outcomes, Public Health and Economics Research Center, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Indian J Ophthalmol. 2023 Feb;71(2):418-423. doi: 10.4103/ijo.IJO_1446_22.
To describe the demographics, clinical profile, and outcomes of ocular siderosis in patients presenting to a multi-tier ophthalmology hospital network in India.
This cross-sectional and hospital-based study included 3,082,727 new patients who presented between August 2010 and December 2021. Patients with a clinical diagnosis of ocular siderosis in at least one eye were included.
Overall, 58 eyes of 57 patients (0.002%) were diagnosed with ocular siderosis. The majority were men (96.49%) and had unilateral (98.25%) affliction. The most common age group at presentation was during the third decade of life with 24 patients (42.11%). A clear history of ocular trauma was documented in 47 patients (81.03%). Major clinical signs included corneal pigment deposition in nearly half of the eyes (27/58 eyes, 46.55%), corneal scar (20/58 eyes, 34.48%), cataract (22/58 eyes, 37.93%) and retinal detachment (11/58 eyes, 18.96%). The intraocular foreign body (IOFB) was anatomically localized in a majority of the eyes (i.e., 45/58 eyes, 77.59%). The most common location of the IOFB was in the posterior segment (22/58 eyes, 37.93%). The eyes that underwent a vitreoretinal surgery with removal of IOFB had a slightly better BCVA (1.0 ± 1.01) when compared to eyes with non-removal of IOFB (1.58 ± 1.00).
Ocular siderosis is a rare sight-threatening entity, with half of the affected eyes exhibiting severe visual impairment. Majority of the eyes in ocular siderosis will have a detectable IOFB. Surgical removal of IOFB may lead to a better visual gain when compared to non-removal.
描述在印度一家多级别眼科医院网络就诊的患者中，眼球铁质沉着症的人口统计学、临床特征和结局。
本横断面和基于医院的研究纳入了 2010 年 8 月至 2021 年 12 月期间就诊的 3082727 名新患者。纳入至少一只眼临床诊断为眼球铁质沉着症的患者。
总体而言，57 例患者的 58 只眼（0.002%）被诊断为眼球铁质沉着症。大多数为男性（96.49%），单侧受累（98.25%）。就诊时最常见的年龄组为第三十年龄组，有 24 例患者（42.11%）。47 例患者（81.03%）有明确的眼部外伤史。主要临床体征包括近半数眼的角膜色素沉着（27/58 眼，46.55%）、角膜瘢痕（20/58 眼，34.48%）、白内障（22/58 眼，37.93%）和视网膜脱离（11/58 眼，18.96%）。大多数眼（即 45/58 眼，77.59%）可明确定位眼内异物（IOFB）的解剖位置。IOFB 最常见的位置在后节（22/58 眼，37.93%）。与未取出 IOFB 的眼相比，接受玻璃体视网膜手术取出 IOFB 的眼的最佳矫正视力（BCVA）略好（1.0±1.01）。
眼球铁质沉着症是一种罕见的威胁视力的疾病，一半受影响的眼睛存在严重的视力损害。眼球铁质沉着症的大多数眼都会有可检测到的 IOFB。与未取出 IOFB 相比，取出 IOFB 可能会导致更好的视力改善。
