Southwest Hospital/Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, China; and.
Key Lab of Visual Damage and Regeneration and Restoration of Chongqing, Chongqing, China.
Retina. 2023 May 1;43(5):793-801. doi: 10.1097/IAE.0000000000003739.
To investigate the predisposing clinical parameters and characteristics of fundus imaging of patients with persistent subretinal fluid (PSF) after successful repair of rhegmatogenous retinal detachment.
A retrospective study recruiting 57 patients was conducted. All patients underwent pars plana vitrectomy with silicone oil tamponade. Patients were divided into two groups: patients presenting PSF by the time of silicone oil removal as PSF group and patients presenting no PSF by the time of silicone oil removal as control group. All patients were followed up for 3 months or longer after primary surgery. Ophthalmic examinations, including fundus photography and optical coherence tomography, were performed.
There were significant differences between the two groups in average age, durations of preoperative symptoms, and type of retinal breaks ( P < 0.05). These clinical parameters showed statistical correlations with PSF ( P < 0.05). The proportions of patients presenting distinctive boundaries of the detached retina on fundus photograph and patients showing a hyperreflective line underlying the detached retina on optical coherence tomography in the PSF group were both significantly higher than the control group ( P < 0.05). The macular detachment heights on optical coherence tomography in the PSF group were significantly lower than the control group ( P < 0.05). These imaging characteristics also showed strong correlations with PSF ( P < 0.05).
This study suggests that patients with PSF have younger age, longer symptom duration, and higher incidence of retinal holes. The distinctive detachment boundary on fundus photograph, lower macular detachment height, and hyperreflective line underlying the detached retina on optical coherence tomography may be the predisposing characteristics of PSF.
探讨孔源性视网膜脱离（RRD）成功修复后持续性视网膜下积液（PSF）患者的易患临床参数和眼底影像学特征。
进行了一项回顾性研究，共纳入 57 例患者。所有患者均接受了经睫状体平坦部玻璃体切除术联合硅油填充术。患者分为两组：硅油取出时出现 PSF 的患者为 PSF 组，硅油取出时无 PSF 的患者为对照组。所有患者均在初次手术后随访 3 个月或更长时间。行眼科检查，包括眼底照相和光学相干断层扫描（OCT）。
两组患者的平均年龄、术前症状持续时间和视网膜裂孔类型存在显著差异（P<0.05）。这些临床参数与 PSF 有统计学相关性（P<0.05）。PSF 组中，有显著更多的患者在眼底照相中呈现出脱离视网膜的边界清晰，且有更多的患者在 OCT 下呈现出脱离视网膜下的高反射线，而对照组中这两个比例均显著较低（P<0.05）。PSF 组的 OCT 黄斑脱离高度显著低于对照组（P<0.05）。这些影像学特征也与 PSF 有很强的相关性（P<0.05）。
本研究表明，PSF 患者年龄更小，症状持续时间更长，且视网膜裂孔发生率更高。眼底照相上清晰的脱离边界、更低的黄斑脱离高度和脱离视网膜下的高反射线可能是 PSF 的易患特征。
