From the Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA.
Department of Hematology and Medical Oncology, Emory University, Atlanta, GA.
Clin Nucl Med. 2023 Apr 1;48(4):e202-e203. doi: 10.1097/RLU.0000000000004565. Epub 2023 Jan 14.
A 62-year-old woman with right-sided invasive lobular breast carcinoma completed external beam radiotherapy 6 weeks before undergoing a 68 Ga-PSMA PET/CT and 18 F-fluciclovine PET/CT scan as part of an ongoing clinical trial (NCT04750473) assessing the performance of these molecular imaging modalities in invasive lobular breast carcinoma. The 68 Ga-PSMA PET/CT demonstrated a band-like area of increased radiotracer uptake in the dome of the right lobe of the liver anteriorly, whereas 18 F-fluciclovine PET/CT done a day later revealed photopenia in the corresponding area of the liver. The external beam radiotherapy plan confirmed that the radiotherapy field overlaid the region of the hepatic discordant radiotracer uptake on the PET/CT scans.
一位 62 岁的右侧浸润性小叶乳腺癌女性患者，在进行 68Ga-PSMA PET/CT 和 18F-氟代赖氨酸 PET/CT 扫描前 6 周完成了外部束放射治疗，这是一项正在进行的临床试验（NCT04750473）的一部分，该试验评估了这些分子成像方式在浸润性小叶乳腺癌中的性能。68Ga-PSMA PET/CT 在前部显示出右肝叶穹顶处放射性示踪剂摄取增加的带状区域，而在一天后进行的 18F-氟代赖氨酸 PET/CT 则显示出肝脏相应区域的放射性稀疏。外部束放射治疗计划证实，放射治疗区域覆盖了 PET/CT 扫描中肝放射性示踪剂摄取不一致的区域。
