From the Department of Nuclear Medicine, The First Hospital of China Medical University, Shenyang, China.
Clin Nucl Med. 2023 Apr 1;48(4):354-355. doi: 10.1097/RLU.0000000000004560. Epub 2023 Jan 14.
Prostate cancer metastasis to the rectal mucosa, a relatively rare metastatic site, leads to a higher clinical stage and poorer prognosis. A 65-year-old man with prostate cancer underwent 18 F-prostate-specific membrane antigen (PSMA) PET/CT for staging. Intense 18 F-PSMA uptake occurred at the primary lesion, bladder, adjacent seminal vesicle, and rectum. PET/CT imaging revealed increased homogeneous round activity of the rectal wall. The final diagnosis was prostate cancer metastasis to the rectal mucosa. This case suggested that 18 F-PSMA PET/CT may assist in locating rare metastases of prostate cancer, with potential value for early staging.
前列腺癌转移至直肠黏膜，是一种相对罕见的转移部位，导致更高的临床分期和更差的预后。一位 65 岁男性因前列腺癌接受 18 F-前列腺特异性膜抗原（PSMA）PET/CT 分期。原发灶、膀胱、相邻精囊和直肠均出现强烈的 18 F-PSMA 摄取。PET/CT 成像显示直肠壁均匀圆形活性增加。最终诊断为前列腺癌转移至直肠黏膜。该病例提示 18 F-PSMA PET/CT 可能有助于定位前列腺癌的罕见转移灶，具有早期分期的潜在价值。
